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GenomicsAcute Stress Induced Increase in Histone H3 Lys 9 Trimetylation in Rat Hippocampus
We utilized ChIP Seq to examine the the genomic localization of the increase in H3K9 trimethylation we had previously observed in the hippocampus as a consequence of acute restraint stress in rats (Hunter et. al PNAS 2009). Rats were restrained for 30 minutes, allowed to recover for 1 hour and then ...
ORGANISM(S): Rattus norvegicus 
2012-11-02 | E-GEOD-41217 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse high and low exploratory genetically identical animals
Genetically identical inbred mice exhibit substantial stable individual variability in exploratory behavior. We used microarrays to look at gene expression differences in the hippocampus in female mice separated by stable differences in exploratory behavior Experiment Overall Design: Balb c/J offsp...
ORGANISM(S): Mus musculus 
2008-10-26 | E-GEOD-11680 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse Balb c/J offspring subjected to postnatal handling vs. controls
Postnatal handling in rodents leads to decreased anxiety-like behavior in adulthood. We used microarrays to look at gene expression differences in the CA1 region of the hippocampus in female mice subjected to postnatal handling compared to controls. Experiment Overall Design: Balb c/J offspring wer...
ORGANISM(S): Mus musculus 
2008-10-26 | E-GEOD-11679 | biostudies-arrayexpress
TranscriptomicsHuman-specific patterns of gene expression in the brain (RNA-Seq)
We identified human-specific gene expression patterns in the brain by comparing expression with chimpanzee and rhesus macaque. DpnII tag-based libraries were generated from human, chimpanzee, and rhesus macaque brain (frontal pole, hippocampus, caudate nucleus), and sequenced using an Illumina Genom...
ORGANISM(S): Pan troglodytes 
2012-09-04 | E-GEOD-33587 | biostudies-arrayexpress
TranscriptomicsmiRNA transcription profiling in Status Epilepticus Induced Epileptogenic Process
miRNA array comparing the transcription profile of control rats and rats after intra-hippocampal pilocarpine-induced Status Epilepticus (PILO-SE).
ORGANISM(S): Rattus norvegicus 
2016-04-28 | E-MTAB-4633 | biostudies-arrayexpress
UnknownChemotherapy options in elderly and frail patients with metastatic colorectal cancer (MRC FOCUS2): an open-label, randomised factorial trial.
Not available
S-EPMC3109515 | biostudies-literature
TranscriptomicsGene Expression Study in Progranulin-Deficient Mice
Study of brain regions from GRN KO, Heterozygous and WT mice at different time points (2-6-9 months) Cortex, cerebellum and hippocampus were dissected and studied at 2-6-9 months from KO (-/-), Het (-/+), and WT (+/+) animals
ORGANISM(S): Mus musculus 
2011-08-31 | E-GEOD-31840 | biostudies-arrayexpress
GenomicsNational Human Genome Research Institute Tumor Sequencing Project (TSP) - Lung Adenocarcinoma

The Tumor Sequencing Project (TSP) Consortium is a collaboration among participants at the Baylor College of Medicine Human Genome Sequencing Center, the Broad Institute Genome Sequencing Platform, the Dana Farber Cancer Institute, the Memorial Sloan-Kettering Cancer Center, the Genome Seque...

phs000144.v1.p1 | EGA
TranscriptomicsPrenatal stress-induced programming of genome-wide promoter DNA methylation in 5-Htt deficient mice
The serotonin transporter (5-HTT) gene-linked polymorphic region has been suggested to play a modulatory role in mediating the effects of early-life stress on psychopathology rendering carriers of the low-expression short (s)-allele more vulnerable to environmental adversity in later life. Here we a...
ORGANISM(S): Mus musculus 
2014-11-18 | E-GEOD-51634 | biostudies-arrayexpress
TranscriptomicsRat model of MTLE: Animals with epilepsy vs animals without epilepsy (codelink)
Neither the molecular basis of the pathologic tendency of neuronal circuits to generate spontaneous seizures (epileptogenicity) nor anti-epileptogenic mechanisms that maintain a seizure-free state are well understood. Here, we performed transcriptomic analysis in the intrahippocampal kainate model o...
ORGANISM(S): Rattus norvegicus 
2011-02-13 | E-GEOD-27166 | biostudies-arrayexpress
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