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ProteomicsInferring Epitopes of a Polymorphic Antigen Amidst Broadly Cross-Reactive Antibodies Using Protein Microarrays: a Study of OspC Proteins of Borrelia burgdorferi
Epitope mapping studies aim to identify the binding sites of antibody-antigen interactions to enhance the development of vaccines, diagnostics and immunotherapeutic compounds. However, mapping is a laborious process employing time- and resource-consuming M-bM-^@M-^Xwet benchM-bM-^@M-^Y techniques o...
ORGANISM(S): Peromyscus leucopus 
2013-04-12 | E-GEOD-45996 | biostudies-arrayexpress
TranscriptomicsSu(Hw) and Shep RIP-seq in Kc and BG3 cell lines
Su(Hw) and Shep RIP-seq in Kc and BG3 cell lines RIP-seq with multiple antibodies to two proteins in two Drosophila cell lines, at least 2 replicates for each IP and input
ORGANISM(S): Drosophila melanogaster 
2014-07-29 | E-GEOD-55894 | biostudies-arrayexpress
ProteomicsDifferent Oligomeric States of the Tumor Suppressor p53 Show Identical Binding Behavior Towards the S100β Homodimer
The tumor suppressor protein p53 is a transcription factor that is referred to as the “guardian of the genome” and plays an important role in cancer development. P53 is active as a tetramer; the S100β homodimer binds to the intrinsically disordered C-terminus of p53, affecting its transcriptional ac...
ORGANISM(S): Escherichia coli 
2022-10-14 | PXD029914 | Pride
Cross-linking Intrinsically disordered proteins Tumor suppressor S100β P53 
UnknownCross-attention enables deep learning on limited omics-imaging-clinical data of 130 lung cancer patients.
Not available
S-EPMC11294841 | biostudies-literature
UnknownThe nicotinic α6 subunit gene determines variability in chronic pain sensitivity via cross-inhibition of P2X2/3 receptors.
Not available
S-EPMC5018401 | biostudies-literature
TranscriptomicsmRNA expression profiles of SK-N-AS neuroblastoma cells with induced ALK-wt, ALK-F1174L or ALK-R1275Q
Establishment of inducible SK-N-AS ALKwt, ALKF1174L and ALKR1275Q cell lines Human neuroblastoma SK-N-AS cells were electroporated with pcDNA6/TR (Invitrogen) using the NeonM-eM-( Transfection System (Life Techologies). Single cell clones were generated using blasticidin (7.5M-eM-5g/ml) and limited ...
ORGANISM(S): homo sapiens 
2015-05-04 | E-MTAB-3207 | biostudies-arrayexpress
UnknownAssociation of outdoor artificial light at night with myopia among Chinese adolescents: a representative cross-sectional study.
Not available
S-EPMC11466777 | biostudies-literature
ProteomicsCandidate disease progression biomarkers in AD
Cross-sectional and longitudinal Analysis of CSF from controls and cases with AD
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2015-07-15 | MSV000079192 | MassIVE
TranscriptomicsTranscription profiling and QTL mapping of 60 mice from an F2 sample segregating for diabetes to generate expression trait correlations and expression quantitative trait locus mapping.
Coordinated regulation of gene expression levels across a series of experimental conditions provides valuable information about the functions of correlated transcripts. To map gene regulatory pathways, we used microarray-derived gene expression measurements in 60 individuals of an F2 sample segregat...
ORGANISM(S): Mus musculus 
2008-06-12 | E-GEOD-3330 | biostudies-arrayexpress
UnknownAssociation of Outdoor Artificial Light at Night With Mental Disorders and Sleep Patterns Among US Adolescents.
Not available
S-EPMC7344797 | biostudies-literature
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