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ProteomicsInferring Epitopes of a Polymorphic Antigen Amidst Broadly Cross-Reactive Antibodies Using Protein Microarrays: a Study of OspC Proteins of Borrelia burgdorferi
Epitope mapping studies aim to identify the binding sites of antibody-antigen interactions to enhance the development of vaccines, diagnostics and immunotherapeutic compounds. However, mapping is a laborious process employing time- and resource-consuming M-bM-^@M-^Xwet benchM-bM-^@M-^Y techniques o...
ORGANISM(S): Peromyscus leucopus 
2013-04-12 | E-GEOD-45996 | biostudies-arrayexpress
MetabolomicsFecal microbiota transplantation plus anti-PD-1 immunotherapy in advanced melanoma: a phase I trial

Fecal microbiota transplantation (FMT) represents a potential strategy to overcome resistance to immune checkpoint inhibitors in patients with refractory melanoma; however, the role of FMT in first-line treatment settings has not been evaluated. We conducted a multicenter phase I trial combining ...

2025-02-27 | MTBLS711 | MetaboLights
UnknownFluorinated Redox-Responsive Cross-Linked Poly(amidoamine) G2 as Smart Theranostic Dendrimers.
Not available
S-EPMC12421505 | biostudies-literature
TranscriptomicsExpression and genomic hybridization data for the Toxoplasma gondii I X III cross
This SuperSeries is composed of the following subset Series: GSE26558: Expression Quantitative Trait Locus (eQTL) Mapping of Stage-specific Gene Expression in Progeny from a type I X III Genetic Cross of Toxoplasma gondii GSE26607: Genomic hybridizations for the parents and progeny of the Toxoplasma...
ORGANISM(S): Toxoplasma gondii 
2012-01-11 | E-GEOD-26608 | biostudies-arrayexpress
TranscriptomicsGenomic hybridizations for the parents and progeny of the Toxoplasma gondii I X III genetic cross
The parents and progeny of the I X III genetic cross were genotyped using the ToxoGeneChip in order to generate a more detailed genetic map. We also used the genomic hybridization data to look for copy number variations (CNV) and segmental duplications. The ToxoGeneChip microarray (http://ancillary...
ORGANISM(S): Toxoplasma gondii 
2012-01-11 | E-GEOD-26607 | biostudies-arrayexpress
TranscriptomicsEffects of 30 days resveratrol supplementation on adipose tissue morphology and gene expression patterns in obese men
Polyphenolic compounds, such as resveratrol, have recently received widespread interest due to their ability to mimic effects of calorie restriction. The objective of the present study was to gain more insight into the effects of 30 days resveratrol supplementation on adipose tissue morphology and u...
ORGANISM(S): Homo sapiens 
2013-09-25 | E-GEOD-42432 | biostudies-arrayexpress
UnknownPreparing for Medical Internship: A Case-Based Strategy to Teach Management of Common Overnight Calls to Students.
Not available
S-EPMC7511063 | biostudies-literature
TranscriptomicsTranscription profiling of S. cerevisiae chemostat cultures limiting for carbon, nitrogen, phosphorus, sulfur under aerobic and anaerobic conditions
The goal of this study was to study this interaction by analyzing genome-wide transcriptional responses to four different nutrient-limitation regimes under aerobic and anaerobic conditions in chemostat cultures of S. cerevisiae. This ‘two-dimensional’ approach resulted in a new, robust set of â€...
ORGANISM(S): Saccharomyces cerevisiae 
2007-07-09 | E-GEOD-1723 | biostudies-arrayexpress
UnknownMedicare Advantage: National Carriers Expand Market Share While Regional Carriers Without Affiliation Decline, 2012-23.
Not available
S-EPMC11813174 | biostudies-literature
TranscriptomicsExpression Quantitative Trait Locus (eQTL) Mapping of Stage-specific Gene Expression in Progeny from a type I X III Genetic Cross of Toxoplasma gondii
The control of gene expression in Toxoplasma is not well understood. As we and others have shown, this organism does contain bipartite promoters that are sufficient to induce gene expression. This information can be used in downstream experiments to identify proteins that bind to experimentally co...
ORGANISM(S): Toxoplasma gondii 
2012-01-11 | E-GEOD-26558 | biostudies-arrayexpress
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