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MetabolomicsHost: Microbiome co-metabolic processing of dietary polyphenols – An acute, single blinded, cross-over study with different doses of apple polyphenols in healthy subjects
Apples are one of the most commonly consumed fruits and their high polyphenol content is considered one of the most important determinants of their health-promoting activities. Here we studied the nutrikinetics of apple polyphenols by UHPLC-HRMS metabolite fingerprinting, comparing the bioavailabili...
2018-10-11 | MTBLS473 | MetaboLights
MetabolomicsPlasma lipidomic profiles after a low and high glycemic load dietary pattern in a randomized controlled cross over feeding study
Not available
ORGANISM(S): Homo sapiens 
ST001490 | MetabolomicsWorkbench
Transcriptomicsgene expression in human subcutaneous adipose tissue after CLA intervention
Iisomer-specific effects of conjugated linoleic (CLA) supplementation on gene expression with particular consideration of the PPAR 2 Pro12Ala SNP in human adipose tissue. Effect of CLA supplementation on genome wide gene expression in adipose tissue biopsies from 5 PPARg2 Ala12Ala and 5 PPARg2 Pro12...
ORGANISM(S): Homo sapiens 
2009-09-01 | E-GEOD-16615 | biostudies-arrayexpress
TranscriptomicsCalorie restriction-like effects of 30 days of resveratrol supplementation on energy metabolism and metabolic profile in obese humans
Resveratrol is a naturally occurring compound that profoundly affects energy metabolism and mitochondrial function and serves as a calorie restriction mimetic, at least in animal models of obesity. Here we treated 10 healthy, obese men with placebo and 150 mg/day resveratrol in a randomized double-b...
ORGANISM(S): Homo sapiens 
2011-11-08 | E-GEOD-32357 | biostudies-arrayexpress
ProteomicsCooking methods affect Advanced Glycation End products and lipid profiles: a randomized cross-over study in healthy subjects
Thermal treatments used in Ultra-Processed Foods (UPFs) lead to advanced glycation end products (AGEs) in food products. UPFs and serum AGEs are both associated with cardiometabolic disease. We explored differential cooking methods as a mechanistic link between UPFs and detrimental health outcomes. ...
ORGANISM(S): Homo sapiens (Human) 
2025-01-24 | PXD059624 | Pride
Human Diet Olink 
Genomicsceae09f4-f021-444d-b025-bee14880fa30 - samples
16S rDNA amplicon sequencing of 196 human fecal samples of an Inulin cross-over trial in healthy, mildly constipated individuals.
EGAD00001004956 | EGA
TranscriptomicsHigh fat challenges with different fatty acids affect distinct atherogenic gene expression pathways in immune cells from lean and obese subjects
Early perturbations in vascular health can be detected by imposing subjects to a high fat (HF) challenge and measure response capacity. Subtle responses can be determined by assessment of whole-genome transcriptional changes. We aimed to magnify differences in health by comparing gene-expression cha...
ORGANISM(S): Homo sapiens 
2015-05-13 | E-GEOD-53232 | biostudies-arrayexpress
TranscriptomicsEpigenetic analysis of healthy young men following a control and high-fat overfeeding diet
Genome-wide DNA methylation profiling of healthy young men following a control and high-fat overfeeding diet using Illumina's Infinium 27k Human DNA methylation Beadchip v. 1.2. DNA methylation profiles were obtained for 27,578 CpG sites in human skeletal muscle. Randomized cross-over desgin, where ...
ORGANISM(S): Homo sapiens 
2012-09-12 | E-GEOD-36166 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of peripheral blood mononuclear cells in healthy young men 6 hours after intake of either saturated fatty acids or polyunsaturated fatty acids
Acute effects of different dietary fatty acids on the gene expression profiles of peripheral blood mononuclear cells in healthy young men. A randomized cross-over study.
ORGANISM(S): Homo sapiens 
2009-11-01 | E-MTAB-65 | biostudies-arrayexpress
TranscriptomicsMucosal responses of healthy humans to three different probiotic Lactobacillus bacteria
Probiotic bacteria, specific representatives of bacterial species that are a common part of the human microbiota, are proposed to deliver health benefits to the consumer by modulation of intestinal function via largely unknown molecular mechanisms. To explore in vivo mucosal responses of healthy adu...
ORGANISM(S): Homo sapiens 
2010-09-08 | E-GEOD-18741 | biostudies-arrayexpress
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