Sort   by:  
 Page size 
ProteomicsPOLR3A Crosslinking co-immunoprecipitate MS
RNA polymerase III (Pol III) produces noncoding RNAs involved in diverse cellular activities, including translation (tRNA, 5S rRNA, 7SL RNA), RNA processing (U6 snRNA, RPPH1, RMRP), and transcription regulation (7SK snRNA). In this way, Pol III activity must be broadly coupled with cellular demands ...
ORGANISM(S): Homo sapiens (Human) 
2026-09-03 | PXD078872 | Pride
Polr3a Crosslinking co-immunoprecipitate 
GenomicsGenome-wide mapping of CarD, RNAPs, and RNAPb on the Mycobacterium smegmatis genome using Chromatin Immunoprecipitation Sequencing
CarD is an essential mycobacterial protein that we had previously shown to bind the RNA polymerase (RNAP) and affect the transcriptional profile of M. smegmatis and Mycobacterium tuberculosis. For this reason, we suspected that CarD was directly regulating transcriptional complexes but we did not kn...
ORGANISM(S): Mycobacterium smegmatis 
2013-08-01 | E-GEOD-48164 | biostudies-arrayexpress
TranscriptomicsIdentification of StpA-binding sites on the Salmonella genome
We used ChIP-chip analysis to identify where the nucleoid associated protein StpA binds on the Salmonella Typhimurium genome. We identified 285 chromosomal regions bound by StpA, ranging in size from 400 to 3500 base pairs and containing 572 genes. Comparison of the ChIP data revealed that StpA disp...
ORGANISM(S): Salmonella enterica subsp. enterica serovar Typhimurium str. SL1344 
2009-10-28 | E-GEOD-18450 | biostudies-arrayexpress
TranscriptomicsMapping of genome-wide action sites of topoisomerase IIbeta by a functional ChIP-chip technique (eTIP-tiling array)
DNA topoisomerase II (topo II) catalyzes a strand passage reaction in that one duplex is passed through a transient brake in another. Completion of late stages of neuronal development depends on the presence of active isoform (topo IIbeta). We identified topo IIbeta action sites on 7 selected genomi...
ORGANISM(S): Rattus norvegicus 
2010-05-15 | E-GEOD-13145 | biostudies-arrayexpress
TranscriptomicsRSC and ISW1 Chromatin Remodelers Display Functional and Chromatin-based Promoter Antagonism [ChIP-chip]
ISWI-family chromatin remodelers organize nucleosome arrays, while SWI/SNF-family remodelers (RSC) disorganize and eject nucleosomes, implying an antagonism that is largely unexplored in vivo. Here, we describe two independent genetic screens for rsc suppressors that yielded mutations in the promote...
ORGANISM(S): Saccharomyces cerevisiae 
2015-04-01 | E-GEOD-65589 | biostudies-arrayexpress
Sort   by:  
 Page size