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TranscriptomicsInnate host defense requires TFEB-mediated transcription of cytoprotective and antimicrobial genes
We report the profiling of induced mRNA transcripts in two C. elegan replicate populations -- WT (N2) and mutant strain with deficient HLH30. Both strains were fed either OP50 strain of e-coli (normal feed) or S. aureus Examination of infected versus uninfected wildtype and mutant lawns of animals
ORGANISM(S): Caenorhabditis elegans 
2015-06-04 | E-GEOD-57739 | biostudies-arrayexpress
UnknownPharmacogenomic associations of adverse drug reactions in asthma: systematic review and research prioritisation.
Not available
S-EPMC7502355 | biostudies-literature
TranscriptomicsEpigenetic and genetic influences on DNA methylation variation in maize populations
DNA methylation is a chromatin modification that is frequently associated with epigenetic regulation in plants and mammals. However, other genetic changes such as transposon insertions also can lead to changes in DNA methylation levels. Genome-wide profiles of DNA methylation levels for 20 maize i...
ORGANISM(S): Zea mays 
2013-08-12 | E-GEOD-46949 | biostudies-arrayexpress
TranscriptomicsSpreading of heterochromatin is limited to specific families of maize retrotransposons
Transposable elements have the potential to act as controlling elements to influence the expression of genes. The current paradigm suggests that heterochromatic silencing can spread beyond the borders of the transposable element and influence the chromatin state of neighboring low-copy sequences. ...
ORGANISM(S): Zea mays 
2012-11-26 | E-GEOD-39460 | biostudies-arrayexpress
TranscriptomicsParent-of-origin effects on gene expression and DNA methylation in the maize endosperm
Imprinting describes the differential expression of alleles based upon their parent of origin. Deep sequencing of RNAs from maize endosperm and embryo tissue 14 days after pollination was used to identify imprinted genes among a set of ~12,000 genes that were expressed and contained sequence polymo...
ORGANISM(S): Zea mays 
2011-12-16 | E-GEOD-33730 | biostudies-arrayexpress
TranscriptomicsChromatin immunoprecipitation of human HeLa cells grown under serum starved conditions to identify new target genes for ETS-domain transcription factor Elk-1
Chromatin immunoprecipitation coupled with microarray analysis (ChIP-chip) was carried out to identify new target genes for ETS-domain transcription factor Elk-1. Experiment was done in Hela cells under serum starved conditions.
ORGANISM(S): Homo sapiens 
2009-08-11 | E-MEXP-2084 | biostudies-arrayexpress
ProteomicsThe Cystatin D Interactome Associated to Systemic Mastocytosis
he aim of the project is to characterize qualitatively and quantitatively the interaction of cystatin D in other protein partner and the formation of a complex in whole saliva of patients affected by different forms of systemic mastocytosis (SM), with and without skin involvement. The different comp...
ORGANISM(S): Homo sapiens (Human) 
2023-10-24 | PXD042567 | Pride
Mastocytosis  high-resolution mass spectrometry  immunoprecipitation assay  cystatin d 
ProteomicsCystatin D-C26 immunocomplex characterization in mastocytosis
Mastocytosis is a myeloproliferative neoplasm characterized by infiltration of clonally derived mast cells in different tissues. According to mast cells localization, it is possible to discriminate cutaneous mastocytosis (CM) from systemic mastocytosis (SM), the latter involving at least an extracut...
ORGANISM(S): Homo sapiens (Human) 
2026-10-07 | PXD015866 | Pride
Hplc-msms Saliva Cystatin d Mastocytosis 
UnknownDesign and methodology of the impact of HemoDiaFIlTration on physical activity and self-reported outcomes: a randomized controlled trial (HDFIT trial) in Brazil.
Not available
S-EPMC6425582 | biostudies-literature
TranscriptomicsA microfluidic device for label-free, physical capture of circulating tumor cell-clusters
Cancer cells metastasize through the bloodstream either as single migratory circulating tumor cells (CTCs) or as multicellular groupings (CTC-clusters). Existing technologies for CTC enrichment are designed primarily to isolate single CTCs, and while CTC-clusters are detectable in some cases, their ...
ORGANISM(S): Homo sapiens 
2015-05-17 | E-GEOD-67939 | biostudies-arrayexpress
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