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UnknownCRYPTIC PRECOCIOUS/MED12 is a novel flowering regulator with multiple target steps in Arabidopsis.
Not available
S-EPMC3278046 | biostudies-literature
TranscriptomicsTranscription profiling of S. cerevisiae Nab3 and Nrd1 mutants
Nrd1 and Nab3 are two yeast RNA binding proteins which have been shown to be involved in transcription termination of non poly(A) genes. We have used expression profiling of a Nab3 mutant to discover novel RNA targets of the Nrd1 and Nab3 transcription termination pathway. Failure to terminate RNA...
ORGANISM(S): Saccharomyces cerevisiae 
2008-06-13 | E-GEOD-4657 | biostudies-arrayexpress
TranscriptomicsDiscovery of a phenotypic switch regulating sexual mating in the opportunistic fungal pathogen Candida tropicalis
Sexual reproduction can promote genetic diversity in eukaryotes, and yet many pathogenic fungi have been labeled as obligate asexual species. It is becoming increasingly clear, however, that cryptic sexual programs may exist in some species, and that efficient mating requires the necessary developme...
ORGANISM(S): Candida tropicalis 
2012-08-28 | E-GEOD-40179 | biostudies-arrayexpress
GenomicsNanoscale Chromatin Profiling of Gastric Adenocarcinoma
To identify chromatin alterations in primary gastric adenocarcionomas, we performed nano-scale chromatin immunoprecipitation-sequencing (Nano-CHiPseq) of histone modifications in 5 gastric cancers and matched normal tissues, We identified hundreds of somatically-altered promoters (marked by H3K4me3)...
ORGANISM(S): Homo sapiens 
2014-07-30 | E-GEOD-51776 | biostudies-arrayexpress
TranscriptomicsCtk1 + CTD mutants
Transcription termination in Saccharomyces cerevisiae can be performed by at least two distinct pathways and is directed by the phosphorylation status of the carboxy-terminal domain (CTD) of RNA polymerase II (Pol II). Late termination of mRNAs is performed by the CPF/CF complex and requires CTD-Ser...
ORGANISM(S): Saccharomyces cerevisiae 
2014-04-22 | E-GEOD-40254 | biostudies-arrayexpress
TranscriptomicsAntisense Cryptic transcription in histone H3 K36A, K56R and K36AK56R mutant yeast strain compared to wild-type
Gene expression microarray experiments to determine the existence of intragenic (cryptic) transcripts in K36A, K56R and K36AK56R mutant yeast strain compared to wildtype. Two color experiment. Mutant/WT. Biological replicates=3. Hybridisation of same samples to strand-specific gene expression arrays...
ORGANISM(S): Saccharomyces cerevisiae 
2012-07-24 | E-GEOD-37042 | biostudies-arrayexpress
TranscriptomicsSense Cryptic transcription in histone H3 K36A, K56R and K36AK56R mutant yeast strain compared to wild-type
Gene expression microarray experiments to determine the existence of intragenic (cryptic) transcripts in K36A, K56R and K36AK56R mutant yeast strain compared to wildtype. Two color experiment. Mutant/WT. Biological replicates=3. Hybridisation of same samples to strand-specific gene expression arrays...
ORGANISM(S): Saccharomyces cerevisiae 
2012-07-24 | E-GEOD-37102 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of SET-2 deletion and wild type yeast on sense and anti-sense arrays
The presence of Set2-mediated methylation of H3K36 (K36me) correlates with transcription frequency throughout the yeast genome. K36me targets the Rpd3S complex to deacetylate transcribed regions and suppress cryptic transcription initiation at certain genes. Here, using a genome-wide approach, we r...
ORGANISM(S): Saccharomyces cerevisiae 
2009-03-03 | E-TABM-265 | biostudies-arrayexpress
GenomicsHistone variant H3.3-specific readout of H3K36 trimethylation by ZMYND11 links transcription elongation control to tumour suppression
Recognition of modified histones by “reader” proteins plays a critical role in the regulation of transcription1. H3K36 trimethylation (H3K36me3) is deposited onto the nucleosomes in the transcribed regions following RNA polymerase II (Pol II) elongation. In yeast, this mark in turn recruits epigenet...
ORGANISM(S): Homo sapiens 
2014-02-24 | E-GEOD-48423 | biostudies-arrayexpress
UnknownEndocrinopathies in a boy with cryptic copy-number variations on 4q, 7q and Xp.
Not available
S-EPMC4785576 | biostudies-literature
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