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TranscriptomicsToward an integrated model of capsule regulation in Cryptococcus neoformans
This SuperSeries is composed of the following subset Series: GSE31911: Cryptococcal H99 cells grown in 8 conditions for capsule induction GSE32049: RNA-Seq analysis of ada2?, nrg1? and cir1? and KN99? wildtype cells in capsule inducing and non-inducing conditions GSE32075: ChIP-Seq of H3K9 acetylati...
ORGANISM(S): Cryptococcus neoformans 
2011-12-10 | E-GEOD-32228 | biostudies-arrayexpress
TranscriptomicsRNA-Seq analysis of ada2M-NM-^T, nrg1M-NM-^T and cir1M-NM-^T and KN99M-NM-1 wildtype cells in capsule inducing and non-inducing conditions
To contextualize the cryptococcal Spt-Ada-Gcn5 Acetyltransferase (SAGA) member Ada2 in the capsule regulatory network, RNA-Seq was performed on wildtype, ada2M-NM-^T and two other transcription factors, nrg1M-NM-^T and cir1M-NM-^T, which like ada2M-NM-^T are also defective for capsule formation, vir...
ORGANISM(S): Cryptococcus neoformans 
2012-01-01 | E-GEOD-32049 | biostudies-arrayexpress
TranscriptomicsCryptococcal H99 cells grown in 8 conditions for capsule induction
To understand the relationship between gene expression and capsule formation, H99 cells were cultured overnight at 37ºC in the following eight conditions: low iron medium with or without both 500 mM ethylenediaminetetraacetic acid (EDTA) and 10 mM bathophenanthroline disulfonate (BPDS); phosphate-bu...
ORGANISM(S): Cryptococcus neoformans 
2012-01-01 | E-GEOD-31911 | biostudies-arrayexpress
TranscriptomicsRNA-Seq analysis of ada2Δ, nrg1Δ and cir1Δ and KN99α wildtype cells in capsule inducing and non-inducing conditions
To contextualize the cryptococcal Spt-Ada-Gcn5 Acetyltransferase (SAGA) member Ada2 in the capsule regulatory network, RNA-Seq was performed on wildtype, ada2Δ and two other transcription factors, nrg1Δ and cir1Δ, which like ada2Δ are also defective for capsule formation, virulence and filamentation...
ORGANISM(S): Cryptococcus neoformans 
2012-01-01 | GSE32049 | GEO
TranscriptomicsUsv101 is a key regulator of cryptococcal virulence and determinant of host response
Cryptococcus neoformans is a fungal pathogen responsible for hundreds of thousands of deaths per year. Its critical virulence factor is a polysacharride capsule which grows large upon entry into a mammalian host. We previously identified USV101 as a transcription factor whose deletion results in enl...
ORGANISM(S): Cryptococcus neoformans 
2016-03-31 | E-GEOD-69532 | biostudies-arrayexpress
TranscriptomicsComparison of transcription profiles of C. neoformans during rabbit or human infection
Ubiquitination is a reversible protein modification involved in various cellular processes in eukaryotic cells. Deubiquitinating enzymes, the proteins responsible for the removal of ubiquitin, act as essential regulators to maintain ubiquitin homeostasis and to exquisitely regulate protein degrada...
ORGANISM(S): Cryptococcus neoformans 
2012-04-10 | E-GEOD-36183 | biostudies-arrayexpress
UnknownCryptococcal xylosyltransferase 1 (Cxt1p) from Cryptococcus neoformans plays a direct role in the synthesis of capsule polysaccharides.
Not available
S-EPMC2386922 | biostudies-literature
TranscriptomicsCryptococcal H99 cells grown in 8 conditions for capsule induction
To understand the relationship between gene expression and capsule formation, H99 cells were cultured overnight at 37ºC in the following eight conditions: low iron medium with or without both 500 mM ethylenediaminetetraacetic acid (EDTA) and 10 mM bathophenanthroline disulfonate (BPDS); phosphate-bu...
ORGANISM(S): Cryptococcus deneoformans Cryptococcus neoformans 
2012-01-01 | GSE31911 | GEO
UnknownSac1 links phosphoinositide turnover to cryptococcal virulence.
Not available
S-EPMC10827209 | biostudies-literature
UnknownSac1 links phosphoinositide turnover to cryptococcal virulence.
Not available
S-EPMC11323556 | biostudies-literature
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