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TranscriptomicsEffect of cigarette smoke on gene expression in mammary epithelial cells [gene expression]
Recent epidemiological studies demonstrate that both active and involuntary exposure to tobacco smoke increases the risk of breast cancer. Little is known, however, about the molecular mechanisms by which tobacco smoke contributes to breast carcinogenesis. To investigate these mechanisms we have ana...
ORGANISM(S): Homo sapiens 
2013-08-12 | E-GEOD-42667 | biostudies-arrayexpress
GenomicsTMB in CSE versus control cohort
TMB in CSE versus control cohort
PRJEB108886 | ENA
TranscriptomicsIdentification of the Candida albicans Cap1p regulon (Cap1-CSE-HA and Cap1-HA complete datasets)
Cap1p, a transcription factor of the basic region-leucine zipper family, regulates oxidative stress response (OSR) in Candida albicans. Alteration of its C-terminal cysteine-rich domain (CRD) results in Cap1p nuclear retention and transcriptional activation. To better understand the function of Ca...
ORGANISM(S): Candida albicans 
2010-05-18 | E-GEOD-15104 | biostudies-arrayexpress
ProteomicsCigarette smoke extract-treated alveolar macrophage-derived extracellular vesicles
This project is based upon the fundamental observation that alveolar macrophage-derived extracellular vesicles (AM-EVs), when internalized by neighboring epithelial cells, inhibit their infection by influenza virus. This inhibitory activity of AM-EVs is abolished when AMs are treated with cigarette ...
ORGANISM(S): Mus musculus (Mouse) 
2020-06-09 | PXD019528 | Pride
Extracellular vesicle Alveolar macrophage Cigarette smoke 
TranscriptomicsCSE-induced hydorogen sulfide improves glucose homeostasis and inhibits beta-cell failure in high-fat diet mice
CSE knockout (CSE-KO)mice at age 6 months were fed a high fat diet (HFD) for 8 weeks.we determined the effects of CSE knockdown on beta-cell function and mass in islets from the mice. After 8 weeks of the HFD,blood glucose levels were drasically increaced in CSE-KO mice compared with WT mice. To ass...
ORGANISM(S): Mus musculus 
2013-09-02 | E-GEOD-50458 | biostudies-arrayexpress
GenomicsTime course CSE treatment of primary human bronchospheres
Time course CSE treatment of primary human bronchospheres
PRJNA911824 | ENA
TranscriptomicsMitochondrial mutations in cigarette smoke extract-chronically treated human oral OKF6 cells
The objective of this study was to analyze the mitochondrial mutations induced by chronic cigarette smoke extract treatment in human oral immortal OKF6 cells. The objective of this study was to analyze the mitochondrial mutations induced by chronic cigarette smoke extract treatment in human oral imm...
ORGANISM(S): Homo sapiens 
2011-02-10 | E-GEOD-24414 | biostudies-arrayexpress
GenomicsNovel Epigenetic Mechanisms of Endogenous CSE/H₂S in Smooth Muscle Cells for Abdominal Aortic Aneurysm
Novel Epigenetic Mechanisms of Endogenous CSE/H₂S in Smooth Muscle Cells for Abdominal Aortic Aneurysm
PRJNA1229439 | ENA
GenomicsTranscriptome data on gene expression in Drosophila strains with deletions of sulfur metabolism genes: CBS and CSE
Transcriptome data on gene expression in Drosophila strains with deletions of sulfur metabolism genes: CBS and CSE
PRJNA824439 | ENA
ProteomicsThermal proteome profilling in WT and CSE-/- MEF cells upon H2O2 treatment
Cellular homeostasis relies on precise regulation through chemical processes, such as protein posttranslational modifications and physical processes, such as biomolecular condensation. Aging disrupts this balance, increasing susceptibility to diseases and death. However, the mechanisms behind age-re...
ORGANISM(S): Mus musculus (Mouse) 
2026-05-23 | PXD045820 | Pride
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