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Pyruvate is a central metabolite that connects many metabolic pathways in living organisms. To meet the cellular pyruvate requirements, Escherichia coli most likely has three pyruvate uptake systems, BtsT, YhjX and CstA. Transport studies in intact cells proved that CstA is a high specific pyruvate ...
ORGANISM(S): Escherichia coli 
2020-12-02 | PXD021798 | Pride
Effect of overexpressing CSTA on gene expression of different nasopharyngeal carcinoma (NPC) cells
To investigate the function of CSTA, we established CSTA-overexpressing cell lines.We then performed gene expression profiling analysis using data obtained from RNA-seq of 4 different NPC cells .
ORGANISM(S): Homo sapiens 
2023-02-11 | GSE224765 | GEO
Cystatin A (gene: CSTA), is up-regulated in non-small-cell lung cancer (NSCLC) and dysplastic vs normal human bronchial epithelium. In the context that chronic obstructive pulmonary disease (COPD), a small airway epithelium (SAE) disorder, is independently associated with NSCLC (especially squamous ...
ORGANISM(S): Homo sapiens 
BMI1, a polycomb transcriptional repressor, regulates the cell cycle, stem cells, proliferation, invasion, and apoptosis. However, the specific role of BMI1 in spontaneous abortion (SA) remains unclear. BMI1 expression levels were detected in control and SA tissues by qRT-PCR and immunofluorescence....
ORGANISM(S): Homo sapiens 
2026-05-31 | GSE266639 | GEO
Reduced levels of BMI1 inhibit trophoblast proliferation and migration via the epigenetic enhancement of CSTA and TGFB2 in spontaneous abortion
Two carbon starvation (cst) genes, cstA and yjiY, in Salmonella are predicted to mediate peptide utilization under nutrient stress. However, the mechanistic details of their function and their importance in the context of Salmonella pathogenesis is not addressed. In this study, the transcriptomes of...
ORGANISM(S): Salmonella enterica subsp. enterica serovar Typhimurium 
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