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GenomicsAn integrin α3β1-CSTF3 signaling axis regulates alternative polyadenylation of Mmp9 mRNA
An integrin α3β1-CSTF3 signaling axis regulates alternative polyadenylation of Mmp9 mRNA
PRJNA1419027 | ENA
TranscriptomicsAn integrin α3β1-CSTF3 signaling axis regulates alternative polyadenylation of Mmp9 mRNA
The laminin-binding integrin α3β1 is highly expressed in epidermal keratinocytes, where it coordinates diverse cellular functions and gene expression during skin remodeling. Here, we show that α3β1-MEK/ERK signaling operates in vivo to promote proximal polyadenylation site (PAS) usage in the Mmp9 ge...
ORGANISM(S): Mus musculus 
2026-02-05 | GSE318492 | GEO
UnknownCSTF3 contributes to platinum resistance in ovarian cancer through alternative polyadenylation of lncRNA NEAT1 and generating the short isoform NEAT1_1.
Not available
S-EPMC11187223 | biostudies-literature
TranscriptomicsCRISPR RNA-seq from HepG2 (ENCSR044GQU)
RNA-seq on HepG2 cells treated with a CRISPR gRNA against CSTF3. (CSTF3-BGHcLV29) For data usage terms and conditions, please refer to http://www.genome.gov/27528022 and http://www.genome.gov/Pages/Research/ENCODE/ENCODE_Data_Use_Policy_for_External_Users_03-07-14.pdf
ORGANISM(S): Homo sapiens 
2022-12-04 | GSE219382 | GEO
ProteomicsCHD2 maintains spermatogonial self-renewal by promoting chromatin activity and mRNA stability
Chromodomain Helicase DNA-binding Domain 2 (CHD2), as a chromatin remodeling factor, was shown to be involved in the regulation of gene expression in embryonic development, neurodevelopment and myelopoiesis. However, its role in male germ cell development has not been elucidated. Here, we confirmed ...
ORGANISM(S): Mus musculus (Mouse) 
2023-03-11 | PXD032277 | Pride
Cstf3 Chromatin remodeling Chd2 Spermatogenesis Mrna stability 
UnknownAlternative Polyadenylation in Triple-Negative Breast Tumors Allows NRAS and c-JUN to Bypass PUMILIO Posttranscriptional Regulation.
Not available
S-EPMC5553310 | biostudies-literature
UnknownChromodomain helicase DNA-binding domain 2 maintains spermatogonial self-renewal by promoting chromatin accessibility and mRNA stability.
Not available
S-EPMC9700024 | biostudies-literature
UnknownYTHDC1 as a tumor progression suppressor through modulating FSP1-dependent ferroptosis suppression in lung cancer.
Not available
S-EPMC10733405 | biostudies-literature
TranscriptomicsCHD2 maintains spermatogonial self-renewal by promoting chromatin activity and mRNA stability
Chromodomain Helicase DNA-binding Domain 2 (CHD2), as a chromatin remodeling factor, was shown to be involved in the regulation of gene expression in embryonic development, neurodevelopment and myelopoiesis. However, its role in male germ cell development has not been elucidated. Here, we confirmed ...
ORGANISM(S): Mus musculus 
2022-11-15 | GSE198581 | GEO
UnknownCYC27 Synthetic Derivative of Bromophenol from Red Alga Rhodomela confervoides: Anti-Diabetic Effects of Sensitizing Insulin Signaling Pathways and Modulating RNA Splicing-Associated RBPs.
Not available
S-EPMC6356253 | biostudies-literature
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