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ProteomicsA Critical Role of cTAGE5/MEA6 in Brain Development through Regulation of Trafficking of Cellular Components in Neurons
Normal neural development is essential for the formation of neuronal networks and brain function. cTAGE5/MEA6 plays a critical role in the secretion of proteins. However, its roles in the transport of non-secretory cellular components and in brain development remain unknown. Here, we show that cTAGE...
ORGANISM(S): Mus musculus (Mouse) 
2018-09-18 | PXD010386 | Pride
Ctage5/mea6  brain development  copii  vesicle trafficking 
UnknownMea6/cTAGE5 cooperates with TRAPPC12 to regulate PTN secretion and white matter development.
Not available
S-EPMC10909747 | biostudies-literature
UnknowncTAGE5/MEA6 plays a critical role in neuronal cellular components trafficking and brain development.
Not available
S-EPMC6176567 | biostudies-literature
UnknowncTAGE5/MEA6 Regulates LBR Localization to Maintain Nuclear Envelope Integrity and Safeguard Against Aging.
Not available
S-EPMC12507394 | biostudies-literature
ProteomicscTAGE5/MEA6 regulates LBR transport to maintain nuclear envelope integrity and safeguard against aging
IP-MS of fused MEA6-GFP and the control sample were performed. For MS analyses, peptides were resuspended in 0.1% FA and analyzed by LTQ Orbitrap Elite mass spectrometer (ThermoFisher Scientific) coupled online to an Easy-nLC 1000 (Thermo Fisher Scientific) in the data-dependent mode.
ORGANISM(S): Homo Sapiens 
PXD063263 |
UnknowncTAGE5 deletion in pancreatic β cells impairs proinsulin trafficking and insulin biogenesis in mice.
Not available
S-EPMC5716288 | biostudies-literature
UnknownMea6 controls VLDL transport through the coordinated regulation of COPII assembly.
Not available
S-EPMC5129886 | biostudies-literature
UnknownAblation of <i>Mea6/cTAGE5</i> in oligodendrocytes significantly impairs white matter structure and lipid content.
Not available
S-EPMC11748983 | biostudies-literature
TranscriptomicsSuppression of Transcriptional Drift Extends C. elegans Lifespan by Postponing the Onset of Mortality
Longevity mechanisms increase lifespan by counteracting the effects of aging. However, whether longevity mechanisms counteract the effects of aging continually throughout life, or whether they act during specific periods of life, preventing changes that precede mortality is unclear. Here, we uncover...
ORGANISM(S): Caenorhabditis elegans 
2016-01-06 | E-GEOD-63528 | biostudies-arrayexpress
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