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TranscriptomicsHuman Pancreatic CTCs Express the ECM Protein SPARC
Circulating Tumor Cells (CTCs) are shed from primary tumors into the bloodstream, mediating the hematogenous spread of cancer to distant organs. To determine the relevance of ECM protein expression to human disease, CTCs were isolated from the blood of metastatic PDAC patients and subjected to singl...
ORGANISM(S): Homo sapiens 
2014-09-22 | E-GEOD-60407 | biostudies-arrayexpress
GenomicsCTCs vs. WBCs from a HNSCC patient
CTCs vs. WBCs from a HNSCC patient
PRJNA464373 | ENA
TranscriptomicsIsolation and expression profiling of circulating tumor cells in breast cancer patients part 3
We developed a method to isolate pure circulating tumor cells (CTC). RNA from such CTCs isolated from the peripheral blood of metastatic breats cnacer patients and gene expression was performed using cDNAmicroarray. we used cDNA array to compare gene expression of CTCs with normal epithelial and b...
ORGANISM(S): Homo sapiens 
2014-12-18 | E-GEOD-45964 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of circulating tumor cells (CTC) from peripheral blood from patients with breast and prostate cancer
In many patients with solid tumors circulating tumor cells (CTCs), that form metastases, can be identified in peripheral blood. Detection and characterization of CTCs in cancer patients provide a unique opportunity to predict patient survival, select and monitor the efficacy of treatment as well as...
ORGANISM(S): Homo sapiens 
2005-06-30 | E-MEXP-136 | biostudies-arrayexpress
TranscriptomicsIsolation and expression profiling of circulating tumor cells in breast cancer patients part 2
We developed a method to isolate pure circulating tumor cells (CTC). RNA from such CTCs isolated from the peripheral blood of metastatic breats cnacer patients and gene expression was performed using cDNAmicroarray. we used cDNA array to compare gene expression of CTCs with normal epithelial and b...
ORGANISM(S): Homo sapiens 
2014-12-18 | E-GEOD-45963 | biostudies-arrayexpress
TranscriptomicsMolecular profiling of single circulating tumor cells with diagnostic intention
About 230 clinical trials currently explore the role of circulating tumor cell (CTC) analysis for therapy decisions, but no assays enable comprehensive molecular characterization of CTCs with diagnostic precision. We therefore combined a workflow for CTC enrichment and isolation with 100% purity wit...
ORGANISM(S): Homo sapiens 
2014-11-05 | E-GEOD-58192 | biostudies-arrayexpress
TranscriptomicsIsolation and expression profiling of circulating tumor cells in breast cancer patients part 1
We developed a method to isolate pure circulating tumor cells (CTC). RNA from such CTCs isolated from the peripheral blood of metastatic breast cancer patients and gene expression was performed using cDNAmicroarray. we used cDNA array to compare gene expression of CTCs with normal epithelial and b...
ORGANISM(S): Homo sapiens 
2014-12-18 | E-GEOD-45962 | biostudies-arrayexpress
GenomicsInvestigating the transcriptional regulation of intratumoral hypoxia in CTCs
Investigating the transcriptional regulation of intratumoral hypoxia in CTCs
PRJNA1002322 | ENA
TranscriptomicsImmunomagnetic enrichment and flow cytometric isolation of breast cancer circulating tumor cells (CTCs) for genomic characterization
We developed a novel approach to isolate tumor cells with high purity from blood via immunomagnetic enrichment followed by fluorescence activated cell sorting (IE/FACS) and examined copy number alterations in these cells. Magnetic beads coated with EpCAM mAb were added to blood to enrich for tumor c...
ORGANISM(S): Homo sapiens 
2012-12-31 | E-GEOD-27511 | biostudies-arrayexpress
GenomicsGenome-wide expression microarray data of MCSP- and ABCB5-enriched CTCs
Genome-wide expression microarray data of MCSP- and ABCB5-enriched CTCs
PRJNA450337 | ENA
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