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TranscriptomicsFunctional characterization of human T cell hyporesponsiveness induced by CTLA4-Ig
During activation, T cells integrate multiple signals from APCs and cytokine milieu. The blockade of these signals can have clinical benefits as exemplified by CTLA4-Ig, which blocks interaction of B7 co-stimulatory molecules on APCs with CD28 on T cells. Variants of CTLA4-Ig, abatacept and belatace...
ORGANISM(S): Homo sapiens 
2015-02-17 | E-GEOD-64712 | biostudies-arrayexpress
GenomicsCTLA4-Ig changed the gene expression associated with cellular movement in osteoclast precursors
CTLA4-Ig changed the gene expression associated with cellular movement in osteoclast precursors
PRJNA449394 | ENA
TranscriptomicsFunctional characterization of human T cell hyporesponsiveness induced by CTLA4-Ig
During activation, T cells integrate multiple signals from APCs and cytokine milieu. The blockade of these signals can have clinical benefits as exemplified by CTLA4-Ig, which blocks interaction of B7 co-stimulatory molecules on APCs with CD28 on T cells. Variants of CTLA4-Ig, abatacept and belatace...
ORGANISM(S): Homo sapiens 
2015-02-17 | GSE64712 | GEO
UnknownInnate immune activity as a predictor of persistent insulin secretion and association with responsiveness to CTLA4-Ig treatment in recent-onset type 1 diabetes.
Not available
S-EPMC6182660 | biostudies-literature
TranscriptomicsCTLA4-Ig changed the gene expression associated with cellular movement in osteoclast precursors
To explore comprehensive gene expression changes, we performed an RNA sequence analysis of CX3CR1-EGFP+ cells from calvaria in mice treated with CTLA4-Ig or control IgG.
ORGANISM(S): Mus musculus 
2018-05-06 | GSE112896 | GEO
UnknownFunctional characterization of human T cell hyporesponsiveness induced by CTLA4-Ig.
Not available
S-EPMC4393265 | biostudies-literature
UnknownCTLA4-Ig in B7-1-positive diabetic and non-diabetic kidney disease.
Not available
S-EPMC5003171 | biostudies-literature
UnknownCTLA4-Ig prolongs graft survival specifically in young but not old mice.
Not available
S-EPMC7855762 | biostudies-literature
UnknownSuccessful Treatment of T Cell-Mediated Acute Rejection with Delayed CTLA4-Ig in Mice.
Not available
S-EPMC5609110 | biostudies-literature
UnknownCTLA4-Ig in combination with FTY720 promotes allograft survival in sensitized recipients.
Not available
S-EPMC5414557 | biostudies-literature
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