Sort   by:  
 Page size 
Unknown[Impact of angiotensin-converting enzyme inhibitors and angiotensin receptor blockers on COVID-19 in a western population. CARDIOVID registry].

Introduction and objectives

Coronavirus disease (COVID-19) has been designated a global pandemic by the World Health Organization. It is unclear whether previous treatment with angiotensin-converting enzyme inhibitors (ACEI) and angiotensin receptor blockers (ARB) affects the prognosis of CO...
S-EPMC7368901 | biostudies-literature
UnknownImpact of angiotensin-converting enzyme inhibitors and angiotensin receptor blockers on COVID-19 in a western population. CARDIOVID registry.

Introduction and objectives

Coronavirus disease (COVID-19) has been designated a global pandemic by the World Health Organization. It is unclear whether previous treatment with angiotensin-converting enzyme inhibitors (ACEI) and angiotensin receptor blockers (ARB) affects the prognosis of CO...
S-EPMC7274611 | biostudies-literature
UnknownDehydroisohispanolone as a Promising NLRP3 Inhibitor Agent: Bioevaluation and Molecular Docking.
Dehydroisohispanolone (DIH), is a labdane diterpene that has exhibited anti-inflammatory activity via inhibition of NF-κB activation, although its potential effects on inflammasome activation remain unexplored. This study aims to elucidate whether DIH modulates NLR family pyrin domain-containing pro...
S-EPMC9316970 | biostudies-literature
UnknownSemisynthesis and Inhibitory Effects of Solidagenone Derivatives on TLR-Mediated Inflammatory Responses.
A series of nine derivatives (2⁻10) were prepared from the diterpene solidagenone (1) and their structures were elucidated by means of spectroscopic studies. Their ability to inhibit inflammatory responses elicited in peritoneal macrophages by TLR ligands was investigated. Compo...
S-EPMC6321690 | biostudies-literature
UnknownCharacterizing Factors Associated with Excess Body Weight: A Descriptive Study Using Principal Component Analysis in a Population with Overweight and Obesity.
Obesity is a worldwide epidemic, making it crucial to understand how it can be effectively prevented/treated. Considering that obesity is a multifactorial condition, this article carried out a baseline cross-sectional study of the variables involved in the disorder. Eighty-four subjects with overwei...
S-EPMC11054611 | biostudies-literature
UnknownExploring the anti-inflammatory activity of fupenzic acid using network pharmacology and experimental validation.
Crataegus azarolus L. (Rosaceae), commonly known as Mediterranean hawthorn, has long been valued in Traditional Medicine for treating cardiovascular and inflammation-related diseases, including diabetes, cancer, and rheumatism. Pharmacological benefits of Crataegus azarolus L. are notably linked to ...
S-EPMC12022156 | biostudies-literature
UnknownRelationship between vertical and horizontal force-velocity-power profiles in various sports and levels of practice.
This study aimed (i) to explore the relationship between vertical (jumping) and horizontal (sprinting) force-velocity-power (FVP) mechanical profiles in a large range of sports and levels of practice, and (ii) to provide a large database to serve as a reference of the FVP profile for all sports and ...
S-EPMC6238764 | biostudies-literature
UnknownDifferences between adjusted vs. non-adjusted loads in velocity-based training: consequences for strength training control and programming
Strength and conditioning specialists commonly deal with the quantification and selection the setting of protocols regarding resistance training intensities. Although the one repetition maximum (1RM) method has been widely used to prescribe exercise intensity, the velocity-based training (VBT) metho...
S-EPMC7996068 | biostudies-literature
UnknownCANCER-ASSOCIATED MUTATIONS IN VAV1 TRIGGER VARIEGATED SIGNALING OUTPUTS AND T CELL LYMPHOMAGENESIS
Mutations in VAV1, a gene that encodes a multifunctional protein important for lymphocytes, are found at different frequencies in peripheral T cell lymphoma (PTCL), non-small cell lung cancer and other tumors. However, their pathobiological significance remains unsettled. After cataloguing 51 cancer...
S-SCDT-EMBOJ-2021-108125 | biostudies-other
UnknownCorticosteroid treatment in critically ill patients with severe influenza pneumonia: a propensity score matching study.

Purpose

To determine clinical predictors associated with corticosteroid administration and its association with ICU mortality in critically ill patients with severe influenza pneumonia.

Methods

Secondary analysis of a prospective cohort study of critically ill patients with confirmed ...
S-EPMC7095489 | biostudies-literature
Sort   by:  
 Page size