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UnknownChromosomal characterization of the three subgenomes in the polyploids of Hordeum murinum L.: new insight into the evolution of this complex.
Not available
S-EPMC3862567 | biostudies-literature
ProteomicsUSP7 is a tumor-specific WNT activator for APC-mutated colorectal cancer by mediating B-catenin deu
The tumor suppressor gene adenomatous polyposis coli (APC) is mutated in most colorectal cancers (CRC) resulting in constitutive Wnt activation. To understand the Wnt-activating mechanism of APC mutation, we applied CRISPR/Cas9 technology to engineer various APC-truncated isogenic lines. We find tha...
ORGANISM(S): Homo sapiens (Human) Mus musculus (Mouse) 
2017-11-09 | PXD007947 | Pride
Apc Lfq 
TranscriptomicsExpression and functional validation of new p38α transcriptional targets in tumorigenesis
p38α MAP kinase plays an important tumor suppressor role, which is mediated by both its negative effect on cell proliferation and its pro-apoptotic activity. Surprisingly, most tumor suppressor mechanisms coordinated by p38α have been reported to occur at the post- translational level. This contrast...
ORGANISM(S): Mus musculus 
2011-11-23 | E-GEOD-26762 | biostudies-arrayexpress
TranscriptomicsThe contribution of cohesin-SA1 to chromatin architecture and gene expression in two murine tissues [RNA-seq]
Cohesin, which consists of SMC1, SMC3, Rad21 and either SA1 or SA2, topologically embraces the chromatin fibers to hold sister chromatids together and to stabilize chromatin loops. Increasing evidence indicates that these loops are the organizing principle of higher-order chromatin architecture, whi...
ORGANISM(S): Mus musculus 
2015-04-07 | E-GEOD-59119 | biostudies-arrayexpress
UnknownTailoring the dialysate bicarbonate eliminates pre-dialysis acidosis and post-dialysis alkalosis.
Not available
S-EPMC9494532 | biostudies-literature
GenomicsA unique role of Cohesin-SA1 in gene regulation and development [ChIP-Seq]
Vertebrates have two cohesin complexes that consist of Smc1, Smc3, Rad21/Scc1 and either SA1 or SA2, but their functional specificity is unclear. Mouse embryos lacking SA1 show developmental delay and die before birth. Comparison of the genome wide distribution of cohesin in wild-type and SA1-null c...
ORGANISM(S): Mus musculus 
2012-03-15 | E-GEOD-32319 | biostudies-arrayexpress
TranscriptomicsA unique role of Cohesin-SA1 in gene regulation and development [Expression]
Vertebrates have two cohesin complexes that consist of Smc1, Smc3, Rad21/Scc1 and either SA1 or SA2, but their functional specificity is unclear. Mouse embryos lacking SA1 show developmental delay and die before birth. Comparison of the genome wide distribution of cohesin in wild-type and SA1-null c...
ORGANISM(S): Mus musculus 
2012-03-15 | E-GEOD-32234 | biostudies-arrayexpress
TranscriptomicsA unique role of Cohesin-SA1 in gene regulation and development
This SuperSeries is composed of the following subset Series: GSE32234: A unique role of Cohesin-SA1 in gene regulation and development [Expression] GSE32319: A unique role of Cohesin-SA1 in gene regulation and development [Chip-Seq] Refer to individual Series
ORGANISM(S): Mus musculus 
2012-03-15 | E-GEOD-32320 | biostudies-arrayexpress
UnknownThe Hidden Sexuality of Alexandrium Minutum: An Example of Overlooked Sex in Dinoflagellates.
Not available
S-EPMC4979955 | biostudies-literature
Unknown“Learn and Move” Program for the Management of Chronic Musculoskeletal Pain in Primary Care: A Pilot Study
Not available
S-EPMC12941048 | biostudies-literature
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