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Bone marrow derived macrophages (BMDMs) were cultured from hind limb bone marrow (femur plus tibia) collected from C57Bl/6 mice 7-days after induction of unilateral (left) hind limb ischaemia by ligation of the femoral artery, along with control mice not undergoing surgery, providing 6 control mouse...
ORGANISM(S): Mus musculus 
The aim of the project is to investigate whether endothelial-restricted augmentation of IGF-1 signaling is sufficient to suppress atherogenesis. We generated RNA-seq data from mice with endothelial-restricted over-expression of human wildtype IGF-1R (hIGFREO/ApoE-/-) or a signaling defective K1003R ...
ORGANISM(S): Mus musculus 
HelQ is a 3’-5’ single stranded DNA (ssDNA) dependent helicase part of the Superfamily 2 helicases (SF2) which are characterised by the presence of two motor domains with a RecA-like fold which couples ATP hydrolysis to DNA translocation. The N-terminal domain of HelQ or N-HelQ (~300 amino acids) is...
ORGANISM(S): Homo sapiens (Human) 
2025-05-06 | PXD049246 | Pride
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