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ProteomicsValidation of a novel shotgun proteomic workflow for the discovery of protein-protein interactions: focus on ZNF521
The study of protein-protein interactions is increasingly relying on mass spectrometry (MS). The classical approach of separating immunoprecipitated proteins by SDS-PAGE followed by in-gel digestion is long and labour-intensive. Besides, it is difficult to integrate it with most quantitative MS-base...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2017-03-29 | MSV000080723 | MassIVE
ProteomicsCaspase inhibition restores dopaminergic identity through the PKA–CREB–BDNF axis in Parkinson’s disease neurons
The progressive loss of dopaminergic identity in midbrain neurons is a hallmark of Parkinson’s disease (PD), contributing to synaptic dysfunction and neurodegeneration. However, the molecular mechanisms linking disease-specific stress to dopaminergic transcriptional failure remain poorly understood....
ORGANISM(S): Homo sapiens (Human) 
2026-06-08 | PXD066765 | Pride
Synaptic function Parkinson’s disease Midbrain dopaminergic neurons Neurodegeneration Pka-creb pathway Apoptosis Qvd-oph 
ProteomicsValidation of a novel shotgun proteomic workflow for the discovery of protein-protein interactions: focus on ZNF521
The study of protein-protein interactions is increasingly relying on mass spectrometry (MS). The classical approach of separating immunoprecipitated proteins by SDS-PAGE followed by in-gel digestion is long and labour-intensive. Besides, it is difficult to integrate it with most quantitative MS-base...
ORGANISM(S): Homo sapiens (Human) 
2015-04-07 | PXD001609 | Pride
Ap-ms  interactomics  18o labelling  znf521  znf423  spt16  spt5  nurd core complex  proteomics  mass spectrometry  shotgun proteomics 
ProteomicsShortgun Proteomic analysis of two Bartonella quintana strains
Proteomic analysis two strains of Bartonella quintana using In-solution digestion followed by Stron Cation Exchange (SCX) and RP nano-LC-MS/MS
ORGANISM(S): Bartonella Quintana Jk 31 (ncbitaxon:1134506) Bartonella Quintana (ncbitaxon:803) 
MSV000079310 | MassIVE
UnknownNHC-Ag(I) and NHC-Au(I) Complexes with <i>N</i>-Boc-Protected α-Amino Acidate Counterions Powerfully Affect the Growth of MDA-MB-231 Cells.
Not available
S-EPMC10641922 | biostudies-literature
UnknownProteomic profiling identifies a stromal TGF-β1/podoplanin axis as a driver of colorectal cancer progression.
Not available
S-EPMC12372361 | biostudies-literature
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