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MetabolomicsProduction of chain-extended cinnamoyl compounds by overexpressing two adjacent cluster-situated LuxR regulators in Streptomyces globisporus C-1027

Natural products from microorganisms are important sources for drug discovery. With the development of high-throughput sequencing technology and bioinformatics, a large amount of uncharacterized biosynthetic gene clusters (BGCs) in microorganisms have been found, which show the potential for nove...

2023-09-06 | MTBLS5152 | MetaboLights
TranscriptomicsExpression profiling of long noncoding RNAs and mRNAs in mouse heart, whole blood (WB), and plasma.
Long noncoding RNA profile in the heart, whole blood, and plasma before and heart failure (HF). In the study presented here, we mixed the five pairs of mouse hearts, whole blood, and plasma before and after HF and identified the genome-wide expression level of lncRNAs.
ORGANISM(S): Mus musculus 
2013-11-12 | E-GEOD-48885 | biostudies-arrayexpress
UnknownLight-Inducible Generation of Membrane Curvature in Live Cells with Engineered BAR Domain Proteins.
Not available
S-EPMC7261005 | biostudies-literature
TranscriptomicsTranscriptome analysis of rice pathogen Acidovorax avenae subsp. avenae cultivated in vitro, in vivo and in co-culture with the rice rhizobacterium Burkholderia seminalis
Determining how a bacterial pathogen responds to its host and other bacterial species by altering gene expression is key to understand its pathogenesis and environmental adaption. Here, we used RNA-Seq to comprehensively and quantitatively assess the transcriptional response of the rice bacterial pa...
ORGANISM(S): Acidovorax avenae subsp. avenae RS-1 
2013-09-03 | E-GEOD-50522 | biostudies-arrayexpress
UnknownIdentification of Quantitative Trait Loci Controlling the Development of Prickles in Eggplant by Genome Re-sequencing Analysis.
Not available
S-EPMC8457335 | biostudies-literature
Genomicsena-DATASET-BGI-26-11-2015-07:58:13:440-13 - samples
Esophageal cancer is one of the most aggressive cancers and the sixth leading cause of cancer death worldwide1. Approximately 70% of the global esophageal cancers occur in China and over 90% histopathological forms of this disease are esophageal squamous cell carcinoma (ESCC)2-3. Currently, there ar...
EGAD00001001691 | EGA
GenomicsWhole-genome sequencing in 14 cases and whole-exome sequencing in 90 cases of Chinese ESCC
Esophageal cancer is one of the most aggressive cancers and the sixth leading cause of cancer death worldwide1. Approximately 70% of the global esophageal cancers occur in China and over 90% histopathological forms of this disease are esophageal squamous cell carcinoma (ESCC)2-3. Currently, there ar...
EGAS00001001487 | EGA
UnknownInhibiting both proline biosynthesis and lipogenesis synergistically suppresses tumor growth.
Not available
S-EPMC7062513 | biostudies-literature
UnknownResearch protocol of the efficacy of probiotics for the treatment of alcohol use disorder among adult males: A comparison with placebo and acceptance and commitment therapy in a randomized controlled trial.
Not available
S-EPMC10697511 | biostudies-literature
GenomicsGroup 3 innate lymphoid cells continuously require the transcription factor GATA3 after commitment
GATA3 is indispensable for the development of all IL-7Rα-expressing innate lymphoid cells (ILCs) and maintenance of type 1 ILCs (ILC1s) and type 2 ILCs (ILC2s). However, the importance of low GATA3 expression in type 3 ILCs (ILC3s) is still elusive. Here, we report that GATA3 regulates homeostasis ...
ORGANISM(S): Mus musculus 
2015-11-23 | E-GEOD-71198 | biostudies-arrayexpress
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