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TranscriptomicsHepatic transcription profiling of mice exposed to As and Fe by drinking water
Five-week-old male mice (Mus musculus, ICR) were exposed to single As, single Fe and combined As and Fe for 90 days. A total of 40 mice were randomly assigned to control and three metal-treated groups. Nine mice were applied in every group. For control group, mice were fed with pure water. For three...
ORGANISM(S): Mus musculus 
2013-01-15 | E-MEXP-3763 | biostudies-arrayexpress
UnknownComprehensive analysis of the expression and prognosis for RBR E3 ubiquitin ligases in lung adenocarcinoma.
Not available
S-EPMC9436683 | biostudies-literature
UnknownCharacterization of NAC Gene Family in Ammopiptanthus mongolicus and Functional Analysis of AmNAC24, an Osmotic and Cold-Stress-Induced NAC Gene.
Not available
S-EPMC10886826 | biostudies-literature
MetabolomicsGut microbiota production of trimethyl-5-aminovaleric acid reduces fatty acid oxidation and accelerates cardiac hypertrophy
Numerous studies found intestinal microbiota alterations which are thought to affect the development of various diseases through the production of gut-derived metabolites. However, the specific metabolites and their pathophysiological contribution to cardiac hypertrophy or heart failure progression ...
2021-12-08 | MTBLS3174 | MetaboLights
TranscriptomicsROR1 Can Interact With TCL1 And Enhance Leukemogenesis in EM-BM-5-TCL1 Transgenic Mice
Transcriptome analysis of RNA samples from leukemia cells of ROR1xTCL1 and TCL1 transgenic mice Animals engrafted with ROR1xTCL1 leukemia-cells developed more aggressive disease than mice engrafted with TCL1 leukemia cells. Transcriptome analysis of RNA samples from leukemia ROR1xTCL1 transgenic mi...
ORGANISM(S): Mus musculus 
2014-01-02 | E-GEOD-51420 | biostudies-arrayexpress
ProteomicsRegulation of Cortical Neurogenesis by MED13L via Transcriptional Priming and its Implications for MED13L Syndrome
MED13L is highly susceptible to neurodevelopmental disorders, yet the underlying developmental mechanisms remain poorly understood. We developed a gene knockout mouse model of MED13L syndrome to elucidate these mechanisms. Homozygous Med13l-null mice exhibit neonatal lethality and severe cortical ne...
ORGANISM(S): Mus musculus (Mouse) 
2025-07-09 | PXD055474 | Pride
Mediator complex Neural progenitors Med13l syndrome Neurogenesis Cerebral cortex 
MetabolomicsPrenatal exposure to trace elements impacts mother-infant gut microbiome, metabolome and resistome during the first year of life

Infancy is a critical period for the colonization of the gut microbiome. However, xenobiotic effects on gut microbiome development in early life remain poorly understood. Here, we recruit 146 mother-infant pairs and collect stool samples at 3, 6, and 12 months after delivery for amplicon sequenci...

2025-05-02 | MTBLS11392 | MetaboLights
ProteomicsGlobal phosphoproteomic analysis of mouse spermatocytes identified key kinases regulating meiosis
Protein phosphorylation, as one of the most important post-translational modifications, exerts crucial roles in regulating meiosis. However, there is a lack of systemic phosphoproteomic and functional analysis of phosphorylation in the meiosis of spermatocytes. To characterize the phosphorylation ev...
ORGANISM(S): Mus Musculus 
2022-03-07 | PXD032089 |
MetabolomicsLactiplantibacillus plantarum PS128 restores microbiota-driven polyamine homeostasis to alleviate autism-like behaviors in Fmr1 knockout mice

Background: Autism spectrum disorder (ASD) is biologically heterogeneous and has limited mechanism-informed interventions targeting core behavioral symptoms. Emerging evidence suggests that gut microbial metabolism shapes neurobehavioral outcomes, yet the specific metabolic pathw...

2026-02-10 | MTBLS13881 | MetaboLights
MetabolomicsLactiplantibacillus plantarum PS128 restores microbiota-driven polyamine homeostasis to alleviate autism-like behaviors in Fmr1 knockout mice

Background Autism spectrum disorder (ASD) is biologically heterogeneous and has limited mechanism-informed interventions targeting core behavioral symptoms. Emerging evidence suggests that gut microbial metabolism shapes neurobehavioral outcomes, yet the specific metabolic pathwa...

2026-02-06 | MTBLS13859 | MetaboLights
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