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UnknownDoes a 6-point scale approach to post-treatment 18F-FDG PET-CT allow to improve response assessment in head and neck squamous cell carcinoma? A multicenter study.

Purpose

Response assessment to definitive non-surgical treatment for head and neck squamous cell carcinoma (HNSCC) is centered on the role of 18F-fluorodeoxyglucose (FDG) positron emission tomography/computed tomography (PET-CT) 12 weeks after treatment. The 5-point Hopkins score ...
S-EPMC8218061 | biostudies-literature
UnknownChemical Characterization of Sauvignon Blanc Wines from Three Cold-Climate-Growing Areas of Chile.
The influence of the geographical location on the chemical composition of commercial Sauvignon Blanc wines was investigated. The assay was carried out on Sauvignon Blanc wines from three cold-climate valleys in Central Chile, Casablanca, Leyda, and San Antonio. The analyses revealed clear variations...
S-EPMC11241741 | biostudies-literature
TranscriptomicsAML with mutated NPM1 carrying a normal or aberrant karyotype show overlapping features
AML with mutated NPM1 usually carries normal karyotype (NK) but it may harbor chromosomal aberrations whose significance remains unclear. We addressed this question in 631 AML patients with mutated/cytoplasmic NPM1. An abnormal karyotype (AK) was present in 93/631 cases (14.7%), the most frequent ab...
ORGANISM(S): Homo sapiens 
2009-06-01 | E-GEOD-16015 | biostudies-arrayexpress
UnknownHigh-flux hemodialysis with polymethylmethacrylate membranes reduces soluble CD40L, a mediator of cardiovascular disease in uremia.

Background and hypothesis

Major adverse cardiovascular events (MACE) are the main cause of mortality in hemodialysis (HD). Soluble CD40 ligand (sCD40L) binds to CD40 on endothelial cells (EC) and vascular smooth muscle cells (VSMC), playing a potential role in MACE. HD registries show a redu...
S-EPMC12559792 | biostudies-literature
UnknownDiagnosis and Management of Cardiovascular Risk in Patients with Polycythemia Vera.
Polycythemia vera (PV) is a myeloproliferative neoplasm characterized by aberrant myeloid lineage hematopoiesis with excessive red blood cell and pro-inflammatory cytokine production. Patients with PV present with a range of thrombotic and hemorrhagic symptoms that affect quality of life and reduce ...
S-EPMC10676644 | biostudies-literature
TranscriptomicsTranscription profiling of human blood from chronic lymphocytic leukemia patients before and after Fludarabine treatment
Transcription profiling of blood from human chronic lymphocytic leukemia patients before and after Fludarabine treatment
ORGANISM(S): Homo sapiens 
2010-09-01 | E-TABM-825 | biostudies-arrayexpress
UnknownChanging Trends in B-Cell Non-Hodgkin Lymphoma Treatment: The Role of Novel Monoclonal Antibodies in Clinical Practice.
We are currently witnessing a dramatic shift in our approach to the treatment of B-cell non-Hodgkin lymphoma (B-NHL). In the evolving clinical landscape, novel treatments for this clinically heterogeneous disease span a wide range of interventions, encompassing targeted agents, cell therapy approach...
S-EPMC10670523 | biostudies-literature
TranscriptomicsMicroRNA profiling of blood from human chronic lymphocytic leukemia patients before and after Fludarabine treatment
Molecular profile of Fludarabine refractory and sensitive CLLs
ORGANISM(S): Homo sapiens 
2010-09-01 | E-TABM-824 | biostudies-arrayexpress
UnknownRandomized trial comparing standard vs sequential high-dose chemotherapy for inducing early CR in adult AML.
Here we evaluated whether sequential high-dose chemotherapy (sHD) increased the early complete remission (CR) rate in acute myelogenous leukemia (AML) compared with standard-intensity idarubicin-cytarabine-etoposide (ICE) chemotherapy. This study enrolled 574 patients (age, 16-73 years; median, 52 y...
S-EPMC6457212 | biostudies-literature
UnknownPatterns of neutralizing humoral response to SARS-CoV-2 infection among hematologic malignancy patients reveal a robust immune response in anti-cancer therapy-naive patients.
Understanding antibody-based SARS-CoV-2 immunity in hematologic malignancy (HM) patients following infection is crucial to inform vaccination strategies for this highly vulnerable population. This cross-sectional study documents the anti-SARS-CoV-2 humoral response and serum neutralizing activity in...
S-EPMC8764505 | biostudies-literature
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