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Transcriptomics17beta-estradiol (E2)-regulated gene expression across time in estrogen-dependent and estrogen deprivation-resistant MCF-7-derived breast cancer cell lines.
A series of MCF-7 variants were previously developed that are either estrogen-dependent for growth (MCF-7:WS8 cells), or resistant to estrogen deprivation and refractory (MCF-7:2A) or sensitive (MCF-7:5C) to E2-induced apoptosis. To identify genes associated with E2-induced apoptosis, estrogen depri...
ORGANISM(S): Homo sapiens 
2011-11-21 | E-GEOD-29917 | biostudies-arrayexpress
Transcriptomics29 untreated breast cancer cell lines vs. pool of all 29 cell lines.
Expression profiling of 29 untreated breast cancer cell lines using Agilent 4x44K V1 (G4112F) dual color oligonucleotide microarrays The primary study objective was to establish a research resource for comparative transcriptomic analysis of a series of commercially available breast cancer cell lines...
ORGANISM(S): Homo sapiens 
2013-11-27 | E-GEOD-51086 | biostudies-arrayexpress
TranscriptomicsDeep Clonal Profiling of Formalin-Fixed Paraffin-Embedded Clinical Samples
Formalin-fixed paraffin-embedded (FFPE) tissues are a vast resource of annotated clinical samples. As such, they represent highly desirable and informative materials for the application of high-definition genomics for improved patient management and to advance the development of personalized therape...
ORGANISM(S): Homo sapiens 
2012-12-31 | E-GEOD-40299 | biostudies-arrayexpress
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