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UnknownMaintaining Interrater Agreement of Core Assessment Instruments in a Multisite Randomized Controlled Clinical Trial: The Randomized Evaluation of Sedation Titration for Respiratory Failure (RESTORE) Trial.
Not available
S-EPMC5488692 | biostudies-literature
ProteomicsProteomics analysis of muscles from long lived O1/O3 flies in young and old age (Circadian gene variants and the skeletal muscle circadian clock contribute to the evolutionary divergence in longevity across Drosophila populations) Liam C. Hunt, Jianqin Jiao, Yong-Dong Wang, David Finkelstein, Deepti Rao, Michelle Curley, Maricela Robles-Murguia, Abbas Shirinifard, Vishwajeeth R. Pagala, Junmin Peng, Yiping Fan, and Fabio Demontis. Genome Research In press 2019.
Protein expression profiles in the whole tissue lysate extracted from the thorax of O1 and O3 long-lived flies with the control B3 strain flies and analyzed by tandem mass tag (TMT)–based mass spectrometry.
ORGANISM(S): Drosophila melanogaster (Fruit fly) 
2019-06-13 | PXD014223 | Pride
Genomic analyses of aging  evolution of aging  circadian muscle transcriptome  longevity  circadian cycle  skeletal muscle  sarcopenia  proteostasis  timeless  drosophila 
TranscriptomicsTranscription profiling of human melanoma cell lines treated with 5-Aza-2-deoxycytidine to identify novel tumor suppressor genes silenced by methylation in melanoma
Malignant melanoma is a common and frequently lethal disease. Current therapeutic interventions have little effect on survival, emphasizing the need for a better understanding of the genetic, epigenetic, and phenotypic changes in melanoma formation and progression. We identified genes that were not ...
ORGANISM(S): Homo sapiens 
2008-06-16 | E-GEOD-9118 | biostudies-arrayexpress
UnknownIndigenous Peoples and research: self-determination in research governance.
Not available
S-EPMC10685893 | biostudies-literature
UnknownPreclinical Evaluation of Long-Acting Emtricitabine Semi-Solid Prodrug Nanoparticle Formulations.
Not available
S-EPMC10383755 | biostudies-literature
TranscriptomicsBeta-catenin Controls Metastasis in Braf-activated Pten-inactivated Melanomas
Malignant melanoma is characterized by frequent metastasis, however specific changes that regulate this process have not been clearly delineated. Although it is well known that Wnt signaling is frequently dysregulated in melanoma, the functional implications of this observation are unclear. By modul...
ORGANISM(S): Mus musculus 
2011-10-12 | E-GEOD-32907 | biostudies-arrayexpress
TranscriptomicsNovel mutations target distinct subgroups of medulloblastoma.
Medulloblastoma is a malignant childhood brain tumour comprising four discrete subgroups. To identify mutations that drive medulloblastoma we sequenced the entire genomes of 37 tumours and matched normal blood. One hundred and thirty-six genes harbouring somatic mutations in this discovery set wer...
ORGANISM(S): Homo sapiens 
2012-07-05 | E-GEOD-37418 | biostudies-arrayexpress
GenomicsThe Genomic Analysis of Medulloblastoma

Medulloblastoma is a heterogenous disease made up of at least four distinct subtypes of disease which appear to exploit and disrupt naturally occurring developmental pathways of cellular growth and hindbrain development. To better understand the driver mutations of this disease, we performed whol...

phs000409.v1.p1 | EGA
UnknownComprehensive genomic characterization of squamous cell lung cancers.
Not available
S-EPMC3466113 | biostudies-literature
UnknownThe Molecular Taxonomy of Primary Prostate Cancer.
Not available
S-EPMC4695400 | biostudies-literature
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