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ProteomicsCharacterization of the Zein Protein Composition in Maize Flour Extracts
Highly homogenous zein protein was isolated from maize kernels in an environment-friendly process using 95 % ethanol as solvent. High purity of the zein protein product was determined by SDS PAGE analysis and by 2 D gel electrophoresis followed by MALDI-ToF-MS peptide mass fingerprinting after in-ge...
ORGANISM(S): Zea mays (Maize) 
2019-06-11 | PXD012849 | Pride
Zein proteins Peptide mass fingerprinting Data base search Maize Maldi-ms Custom-built sequence data base Flour 2d gel electrophoresis 
TranscriptomicsCGH data from 58 bladder tumors
We present the first computational approach to reconstruct the sequence of copy number alterations driving carcinogenesis from the analysis of several tumor samples of a same patient. Applied to BAC array-CGH and SNP array data from bladder and breast cancers, this method proved highly valuable to e...
ORGANISM(S): Homo sapiens 
2010-05-19 | E-GEOD-19193 | biostudies-arrayexpress
GenomicsSubtelomeric CTCF and Cohesin binding site organization using improved subtelomere assemblies and a novel annotation pipeline
We investigated the reported binding of telomere associated factor TERF1 and TERF2 to internal telomere sites using ChIP-Seq for these two factors in a lymphoblastoid cell line. We mapped over 40 million reads for each sample to a custom reference genome that incorporates our subtelomere assembly, ...
ORGANISM(S): Homo sapiens 
2014-02-18 | E-GEOD-55053 | biostudies-arrayexpress
TranscriptomicsAntisense Transcripts Impede Uridylation-induced Exonucleolytic Degradation to Generate Guide RNAs
Small non-coding RNA biogenesis typically involves cleavage of structured precursors by RNase III-like endonucleases. However, guide RNAs that direct U-insertion/deletion mRNA editing in mitochondria of trypanosomes maintain 5′ triphosphate characteristic of transcription start site and possess U-...
ORGANISM(S): Trypanosoma brucei 
2016-02-08 | E-GEOD-71292 | biostudies-arrayexpress
GenomicsBase-pair level resolution of the Nasonia vitripennis methylome
The parasitoid wasp Nasonia vitripennis is an emerging genetic model for functional analysis of DNA methylation. Here, we characterize genome-wide methylation at a base-pair resolution, and compare these results to gene expression across five developmental stages and to methylation patterns reported...
ORGANISM(S): Nasonia vitripennis 
2013-08-27 | E-GEOD-43423 | biostudies-arrayexpress
TranscriptomicsUsing RNA-Seq for gene identification, polymorphism detection and transcript profiling in two alfalfa genotypes with divergent cell wall composition in stems
Alfalfa, [Medicago sativa (L.) sativa], a widely-grown perennial forage has potential for development as a cellulosic ethanol feedstock. The application of genomic approaches would advance development of alfalfa as a cellulosic feedstock. However, the genomics of alfalfa, a non-model species, is sti...
ORGANISM(S): Medicago sativa 
2011-04-21 | E-GEOD-26757 | biostudies-arrayexpress
TranscriptomicsDroplet barcoding for single cell transcriptomics applied to embryonic stem cells
Recently, RNA sequencing has achieved single cell resolution, but what is limiting is an effective way to routinely isolate and process large numbers of individual cells for in-depth sequencing, and to do so quantitatively. We have developed a droplet-microfluidic approach for parallel barcoding tho...
ORGANISM(S): Homo sapiens 
2015-05-20 | E-GEOD-65525 | biostudies-arrayexpress
TranscriptomicsSingle nuclei sequencing of human HFpEF (Heart Failure with reduced ejection fraction) and Mice TAC (Transaortic constriction) data
Single-cell transcriptomics has emerged as a powerful technology for understanding cardiovascular diseases, providing valuable insights into transcriptomic changes linked to heart failure, both with and without preserved ejection fraction. However, significant gaps persist in our understanding of th...
ORGANISM(S): Homo sapiens 
2025-10-01 | E-MTAB-14753 | biostudies-arrayexpress
TranscriptomicsAnalysis of copy number profiles of several tumor samples of same patient reveals the successive steps in tumorigenesis
We present the first computational approach to reconstruct the sequence of copy number alterations driving carcinogenesis from the analysis of several tumor samples of a same patient. Applied to BAC array-CGH and SNP array data from bladder and breast cancers, this method proved highly valuable to e...
ORGANISM(S): Homo sapiens 
2010-06-25 | E-GEOD-19195 | biostudies-arrayexpress
TranscriptomicsTranscriptomic responses of zebrafish embryos to sublethal exposure to GenX (HFPO-DA): A 96-Hour RNA-seq Study
GenX (HFPO-DA) is a per- and polyfluoroalkyl substance (PFAS) increasingly used as a replacement for legacy compounds such as PFOA, but its environmental persistence and potential toxicity raise concerns. Traditional chemical risk assessment is time- and resource-intensive and provides limited insig...
ORGANISM(S): Danio rerio 
2026-05-01 | E-MTAB-15674 | biostudies-arrayexpress
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