Cutaneous squamous cell carcinoma

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human metagenome (1)
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Repository

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Burkitts lymphoma (2)
Askin tumor (2)
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Non-small cell lung carcinoma (2)
Colorectal carcinoma (2)
Adrenal gland neuroblastoma (2)
Clear cell renal carcinoma (2)
Cutaneous T-cell lymphoma (2)
Small cell lung carcinoma (2)
B-cell acute lymphoblastic leukemia (2)
Multiple myeloma (2)

Technology Type

Mass Spectrometry (16)
Shotgun proteomics (12)
ILLUMINA, Illumina HiSeq 2500 (2)
Bottom-up proteomics (2)
Data-dependent acquisition (2)
Illumina HiSeq 4000, ILLUMINA (1)
Illumina HiSeq 2500 (1)
NMR spectroscopy (1)
SRM/MRM (1)

Instrument Platform

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2016 (10)
2010 (8)
2009 (6)
2008 (5)
2007 (3)
2004 (1)

CHEBI ID

CHEBI:91242 (1)
CHEBI:15740 (1)
CHEBI:13705 (1)
CHEBI:15361 (1)
CHEBI:30031 (1)
CHEBI:29985 (1)
CHEBI:17634 (1)
CHEBI:22660 (1)
CHEBI:15347 (1)
CHEBI:16236 (1)
CHEBI:30832 (1)
CHEBI:15428 (1)
CHEBI:15971 (1)
CHEBI:30772 (1)
CHEBI:16199 (1)
CHEBI:16919 (1)
CHEBI:27897 (1)
CHEBI:17191 (1)
CHEBI:15603 (1)
CHEBI:17295 (1)
CHEBI:30769 (1)

Metabolite Name

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First Public Date

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Classification

bacteria (1)

Study status

Recruiting (8)
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Study type

Transcription profiling by array (78)
Interventional (15)
Methylation profiling by array (4)
RNA-seq of non coding RNA (4)
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Comparative genomic hybridization by array (3)
RNA-seq of coding RNA (3)
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RNA-seq of non coding RNA from single cells (1)
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Release Date

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2014 (40)
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2011 (24)
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2010 (11)
2009 (11)
2008 (6)
2007 (4)
2006 (2)
2004 (1)
2001 (1)
1999 (1)

Lab affiliation

Amsterdam UMC, Vrije Universiteit Amsterdam, Medical Oncology, Cancer Center Amsterdam, OncoProteomics Laboratory, Amsterdam, Netherlands (1)
Biochemistry, University of Turku, Turku, Finland (1)
Cell cycle lab. Institut de Recerca Biomèdica de Lleida (IRB Lleida). (1)
Centre for Genomic Regulation (CRG) (1)
Department of Life Technologies, University of Turku, Turku, Finland (1)
Head | Department of Dermatology - Westmead Hospital Academic Leader (HDR PGC) | Sydney Medical School Director | Centre for Translational Skin Research (1)
Institute of Dermatology, Chinese Academy of Medical Sciences and Peking Union Medical College (1)
Institute of Molecular Medicine and Cell Research University of Freiburg, Stefan Meier Strasse 17, 79104 Freiburg, Germany (1)
Laboratory for Functional Genome Analysis Genzentrum Ludwig-Maximilians-Universität München Feodor-Lynen-Str. 25 D-81377 München Germany (1)
Moffitt Cancer Center Tampa, FL, USA (1)
Porter School of Environment and Earth Sciences. Tel Aviv University, Tel Aviv, Israel (1)
Professor in Dermatology, Department of Dermatology Westmead Clinical School, Westmead Hospital (1)
Southern Medical University, No. 1023-1063, Shatai South Road, Baiyun District, Guangzhou (1)
Tel-aviv University (1)
Univ. Bordeaux, Bordeaux Proteome, Bordeaux, France (1)
University of Edinburgh (1)

Location

United States (15)
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Japan (1)

Keyword

Pembrolizumab (7)
CRC (4)
CSCC (2)
HNSCC (2)
MSS-CRC (2)
RCC (2)
TNBC (2)
SCCHN (2)
Nivolumab (2)
Immunotherapy (2)
Renal Cell (1)
HPV cancer (1)
Advanced Hepatocellular Carcinoma (1)
Metastatic Castration-resistant Prostate Cancer (1)
KEYNOTE-D13 (1)
AURELIO-04 (1)
Oropharyngeal (1)
IL2 (1)
CcRCC (1)
Intrahepatic (1)
Extrahepatic (1)
Gastroesophageal Junction (1)
Microsatellite Instability-High (1)
Mismatch Repair Deficient (1)
BCC (1)
Tumor Mutation Burden High (1)
TMB-H (1)
Not assigned yet (1)
Not yet assigned (1)
Not yet defined (1)

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Analysis of the gene expression profile in normal human epidermal keratinocytes and cutaneous squamous cell carcinoma cell lines

The incidence of keratinocyte-derived skin cancer, cutaneous squamous cell carcinoma (cSCC) is increasing worldwide making it the second most common metastatic skin cancer. We used microarrays to characterize gene expression profile in normal human epidermal keratinocytes (NHEK) and cSCC cell lines....

ORGANISM(S): Homo sapiens

2015-08-27 | E-GEOD-66359 | biostudies-arrayexpress

Analysis of the gene expression profile in cutaneous squamous cell carcinoma cells after EphB2 knockdown

The role of Eph/ephrin signaling in numerous biological processes has been established. However, Eph/ephrin signaling has been shown to have complex role in tumor progression. The role of EphB2 receptor in the progression of cutaneous squamous cell carcinoma (cSCC) has not been studied before. EphB2...

ORGANISM(S): Homo sapiens

2015-08-27 | E-GEOD-66361 | biostudies-arrayexpress

RNA-Seq whole transcriptome analysis of normal human epidermal keratinocytes and cutaneous squamous cell carcinoma cell lines.

The incidence of keratinocyte-derived skin cancer, cutaneous squamous cell carcinoma (cSCC) is increasing worldwide making it the second most common metastatic skin cancer. In this project we used SOLiD next generation sequencing to characterize gene expression profiles in normal human epidermal ker...

ORGANISM(S): Homo sapiens

2015-08-27 | E-GEOD-66412 | biostudies-arrayexpress

Microarray analysis of microRNA expression in cutaneous squamous cell carcinoma

MicroRNAs (miRNAs) are a novel class of short RNAs which have shown to be dysregulated in a variety of cancers including squamous cell carcinoma (SCC) of the head&neck. Microarray based miRNA expression profiles of cutaneous SCC (cSCC) however have not been investigated so far. Seven patients with c...

ORGANISM(S): Homo sapiens

2012-10-08 | E-GEOD-34536 | biostudies-arrayexpress

Genomic landscape of carcinogen induced mouse skin squamous cell carcinoma: RNA-sequencing

RNA-sequencing of induced murine squamous cell carcinoma.

ORGANISM(S): Mus musculus

2015-04-16 | E-MTAB-2889 | biostudies-arrayexpress

Transcription profiling of human normal skin, actinic keratosis and squamous cell carcinoma

normal skin (no), actinic keratosis (ak), and squamous cell carcinoma (scc) of the skin were examined:; BACKGROUND: Carcinogenesis is a multi-step process indicated by several genes up- or down-regulated during tumor progression. This study examined and identified differentially expressed genes in c...

ORGANISM(S): Homo sapiens

2007-10-02 | E-GEOD-2503 | biostudies-arrayexpress

EphB2 promotes progression of cutaneous squamous cell carcinoma

This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

ORGANISM(S): Homo sapiens

2015-08-27 | E-GEOD-66368 | biostudies-arrayexpress

TAp63-regulated microRNAs suppress cutaneous squamous cell carcinoma

TAp63 is a transcription factor belonging to the p53 family with important tumor suppressive functions. We show that TAp63-/- mice exhibit an increased susceptibility to UVR-induced cutaneous squamous cell carcinoma (cuSCC). These tumors showed global disruption of miRNA and mRNA expression when com...

ORGANISM(S): Homo sapiens (Human)

2020-07-07 | PXD014261 | Pride

Key differences identified between actinic keratosis and cutaneous squamous cell carcinoma by transcriptome profiling

Cutaneous squamous cell carcinoma (cSCC) is one of the most common malignancies in fair skinned populations worldwide and its incidence is increasing. Despite previous observations of multiple genetic abnormalities in cSCC, the oncogenic process remains elusive. The purpose of this study was to inve...

ORGANISM(S): Homo sapiens

2014-01-21 | E-GEOD-45216 | biostudies-arrayexpress

KGF effects on cutaneous SCC cells

Keratinocyte growth factor (KGF, fibroblast growth factor-7) is a fibroblast-derived mitogen, which stimulates proliferation of epithelial cells. The expression of KGF by dermal fibroblasts is induced following injury and it promotes wound repair. However, the role of KGF in cutaneous carcinogenesis...

ORGANISM(S): Homo sapiens

2012-05-01 | E-GEOD-34652 | biostudies-arrayexpress

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