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TranscriptomicsSOX7-enforced expression promotes the expansion of adult blood progenitors and blocks B cell development
Here we use a microarray approach to define at the molecular level the consequences of SOX7-mediated effect on B lymphopoiesis and progenitor proliferation. Transcriptome profiling analysis was performed on two subpopulations expressing low and high level of SOX7::GFP. Bone marrow cells extracted fr...
ORGANISM(S): Mus musculus 
2016-08-09 | E-GEOD-65552 | biostudies-arrayexpress
TranscriptomicsExpression profiles of human primary osteoblasts (HOB) and MET transformed osteoblast clones
We studied MET-transformed human primary osteoblasts (MET-HOBs), which we previously turned into osteosarcoma cells by LV driven over-expression of MET oncogene. We obtained distinct MET transformed HOB clones derived from independent events of transgene integration. To characterise the phenotype o...
ORGANISM(S): Homo sapiens 
2013-02-28 | E-GEOD-28256 | biostudies-arrayexpress
TranscriptomicsExpression profiles osteosarcoma cell lines and MET transformed osteoblast clones
We studied MET-transformed human primary osteoblasts (MET-HOBs), which we previously turned into osteosarcoma cells by LV driven over-expression of MET oncogene. We obtained distinct MET transformed HOB clones derived from independent events of transgene integration. To characterise the phenotype o...
ORGANISM(S): Homo sapiens 
2013-02-28 | E-GEOD-28252 | biostudies-arrayexpress
TranscriptomicsRNA-seq of WT and fkbp4 crispant Xenopus tadpoles
The airm of the approach was to identify genes in whole Xenopus tadpoles (Stage NF42) that are upregulated or downregulated due to disruption of the fkbp4 by CRISPR-Cas9 gene editing compared to control tadpoles. Xenopus fkbp4 crispants were generated to make a model of a novel human syndrome caused...
ORGANISM(S): Xenopus tropicalis 
2026-10-29 | E-MTAB-17717 | biostudies-arrayexpress
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