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TranscriptomicsIntegrator complex regulates NELF-mediated RNA Polymerase II pause/release and processivity at coding genes.
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Homo sapiens 
2015-05-19 | E-GEOD-60586 | biostudies-arrayexpress
TranscriptomicsInsulators recruit histone methyltransferase dMes4 to regulate chromatin of flanking genes
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Drosophila melanogaster 
2014-04-30 | E-GEOD-57168 | biostudies-arrayexpress
TranscriptomicsNext Generation Sequencing analysis of Functional Interactions among Insulator Proteins
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Drosophila melanogaster 
2014-02-01 | E-GEOD-52887 | biostudies-arrayexpress
GenomicsIntegrator complex regulates NELF-mediated RNA Polymerase II pause/release and processivity at coding genes [ChIP-seq]
RNAPII pausing/termination shortly after initiation is a hallmark of gene regulation. However, the molecular mechanisms involved are still to be uncovered. Here, we show that NELF interacts with Integrator complex subunits (INTScom) forming a stable complex with RNPII and Spt5. The interaction betwe...
ORGANISM(S): Homo sapiens 
2015-05-19 | E-GEOD-60584 | biostudies-arrayexpress
TranscriptomicsIntegrator complex regulates NELF-mediated RNA Polymerase II pause/release and processivity at coding genes [RNA-seq]
RNAPII pausing/termination shortly after initiation is a hallmark of gene regulation. However, the molecular mechanisms involved are still to be uncovered. Here, we show that NELF interacts with Integrator complex subunits (INTScom) forming a stable complex with RNPII and Spt5. The interaction betwe...
ORGANISM(S): Homo sapiens 
2015-05-19 | E-GEOD-60585 | biostudies-arrayexpress
UnknownCytotoxic and Anti-Inflammatory Effects of Ent-Kaurane Derivatives Isolated from the Alpine Plant Sideritis hyssopifolia.
Not available
S-EPMC7037520 | biostudies-literature
GenomicsNext Generation Sequencing analysis of Functional Interactions among Insulator Proteins [CP190 ChIP-Seq]
Eukaryotic chromosomes are partitioned into topologically associating domains (TADs) that are demarcated by distinct insulator-binding proteins (IBPs) in Drosophila. Whether IBPs regulate specific long-range contacts and how this may impact gene expression remains unclear. Here we identify ‘indirect...
ORGANISM(S): Drosophila melanogaster 
2014-02-01 | E-GEOD-52886 | biostudies-arrayexpress
TranscriptomicsNext Generation Sequencing analysis of Functional Interactions among Insulator Proteins [RNA-Seq]
Eukaryotic chromosomes are partitioned into topologically associating domains (TADs) that are demarcated by distinct insulator-binding proteins (IBPs) in Drosophila. Whether IBPs regulate specific long-range contacts and how this may impact gene expression remains unclear. Here we identify M-bM-^@M-...
ORGANISM(S): Drosophila melanogaster 
2014-02-01 | E-GEOD-52884 | biostudies-arrayexpress
GenomicsIllumina Sequencing data of Insulator Proteins and the co-factor dMes-4
The Drosophila insulator-binding proteins (IBPs) dCTCF/Beaf32 mark the physical borders of chromosomal domains involving co-factors that participate in long-range interactions. Chromosomal borders are further enriched in specific histone modifications yet the implication of histone modifiers and nuc...
ORGANISM(S): Drosophila melanogaster 
2014-04-30 | E-GEOD-57165 | biostudies-arrayexpress
GenomicsNext Generation Sequencing analysis of Functional Interactions among Insulator Proteins [Beaf-32 ChIP-seq]
Eukaryotic chromosomes are partitioned into topologically associating domains (TADs) that are demarcated by distinct insulator-binding proteins (IBPs) in Drosophila. Whether IBPs regulate specific long-range contacts and how this may impact gene expression remains unclear. Here we identify ‘indirect...
ORGANISM(S): Drosophila melanogaster 
2014-02-01 | E-GEOD-52962 | biostudies-arrayexpress
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