Sort   by:  
 Page size 
ProteomicsCUX1 recruits SWI/SNF to promote chromatin accessibility in human hematopoietic cells
Transcription factors(TF) plays a key role in hematopoiesis via promoting cell-type specific gene expression. A subset of TFs, canonically termed “pioneer factors”, possesses the ability to bind to otherwise inaccessible heterochromatin regions, and recruit additional TFs, co-activators, and chromat...
ORGANISM(S): Homo sapiens (Human) 
2026-03-16 | PXD037838 | Pride
Human Q-exactive Ip-ms Cux1 Swi/snf Chromatin 
ProteomicsGenomic studies controvert the existence of the CUX1 p75 isoform
CUX1, a homeodomain-containing transcription factor, is recurrently deleted or mutated in multiple tumor types. In myeloid neoplasms, CUX1 deletion or mutation carries a poor prognosis. We have previously established that CUX1 functions as a tumor suppressor in hematopoietic cells across multiple or...
ORGANISM(S): Homo sapiens (Human) 
2022-02-17 | PXD027527 | Pride
Q-exactive Human Cux1 Kg-1 cell line 
TranscriptomicsTranscription profiling : Stable knockdown CUX1 knockdown in LOUCY cells lines
LOUCY cells were resuspended in Opti-MEM (Gibco) and electroporated in 4 mm cuvettes (300 V, 1000 F; Genepulser XCell, Bio-Rad) using Stealth siRNAs (Ambion) against CUX1 or negative control duplexes. Cells were rested for 15 min following electroporation before dilution into normal RPMI 10 percent ...
ORGANISM(S): Homo sapiens 
2013-11-05 | E-MTAB-1833 | biostudies-arrayexpress
GenomicsATAC-Seq of sorted murine LT-HSCs segemented on intial CUX1 levels with and without CUX1 knockdown.
ATAC-Seq of sorted murine LT-HSCs segemented on intial CUX1 levels with and without CUX1 knockdown.
PRJNA1144495 | ENA
GenomicsRNA-seq of sorted murine long-term hematopoietic stem cells segmented on CUX1 levels with and without CUX1 knockdown
RNA-seq of sorted murine long-term hematopoietic stem cells segmented on CUX1 levels with and without CUX1 knockdown
PRJNA1144496 | ENA
GenomicsNext generation sequencing following CUX1 knockdown in erythroblasts
Next generation sequencing following CUX1 knockdown in erythroblasts
PRJNA752767 | ENA
GenomicsCUX1 deficiency potentiates RAS signaling to drive malignancy
CUX1 deficiency potentiates RAS signaling to drive malignancy
PRJNA678951 | ENA
GenomicsTranscriptomic analysis of neuroblastoma cells in response to stable over-expression of circular RNA derived from CUX1 gene (circ-CUX1)
Transcriptomic analysis of neuroblastoma cells in response to stable over-expression of circular RNA derived from CUX1 gene (circ-CUX1)
PRJNA561358 | ENA
GenomicsReduction of di-methyl histone H3K9 (H3K9me2) in CUX1-deficient cells.
Reduction of di-methyl histone H3K9 (H3K9me2) in CUX1-deficient cells.
PRJNA1268428 | ENA
GenomicsATAC-Seq of sorted murine LT-HSCs segemented on intial CUX1 levels with and without CUX1 knockdown.
Hematopoietic stem cells (HSCs) possess properties of both self-renewal and multipotent differentiation; however, the regulation of these opposing properties remains elusive. Using a novel reporter mouse, we demonstrate the dose-dependent role of the transcription factor, CUX1, in HSC fate. As CUX1 ...
ORGANISM(S): Mus musculus 
2025-08-01 | GSE274032 | GEO
Sort   by:  
 Page size