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Cyclic di-GMP (c-di-GMP) is a well-known second messenger that plays a key role in many physiological processes in bacteria. The synthesis of lipids is essential for bacterial biofilm formation. However, whether c-di-GMP signaling modulates the synthesis of lipid and further regulates biofilm for...

2023-12-12 | MTBLS7053 | MetaboLights
Cyclic di-GMP (c-di-GMP) is a ubiquitous second messenger that regulates many biological processes in bacteria. The genome in Mycobacterium tuberculosis encodes a single copy of the diguanylate cyclase gene (dgc) responsible for c-di-GMP synthesis. To determine the role of c-di-GMP signaling in M. t...
ORGANISM(S): Mycobacterium tuberculosis 
The innate immune system responds to unique molecular signatures that are widely conserved among microbes but that are not normally present in host cells. Compounds that stimulate innate immune pathways may be valuable in the design of novel adjuvants, vaccines, and other immunotherapeutics.The cyc...
ORGANISM(S): Mus musculus 
Cyclic di-GMP Regulates Shigella flexneri Pathogenesis
Elevated intracellular cyclic-di-GMP level in Shewanella oneidensis increases expression of c-type cytochromes
Genomics
cyclic-di-gmp-modulation
Cyclic di-GMP (c-di-GMP) is a ubiquitous second messenger that regulates many biological processes in bacteria. The genome in Mycobacterium tuberculosis encodes a single copy of the diguanylate cyclase gene (dgc) responsible for c-di-GMP synthesis. To determine the role of c-di-GMP signaling in M. t...
ORGANISM(S): Mycobacterium tuberculosis Mycobacterium tuberculosis H37Ra 
2013-10-09 | GSE37973 | GEO
Transcriptomic analysis used to understand the influence of elevated intracellular cyclic-di-GMP in Shewanella oneidensis on expression of c-type cytochrome at transcript level.
ORGANISM(S): Shewanella oneidensis 
2021-01-26 | GSE138586 | GEO
The cyanobacterial phytochrome 2 regulates the expression of motility-related genes through the second messenger cyclic di-GMP
The innate immune system responds to unique molecular signatures that are widely conserved among microbes but that are not normally present in host cells. Compounds that stimulate innate immune pathways may be valuable in the design of novel adjuvants, vaccines, and other immunotherapeutics.The cycl...
ORGANISM(S): Mus musculus 
2009-07-22 | GSE16943 | GEO
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