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MetabolomicsThe genetic origin of evolidine, the first cyclopeptide discovered in plants, and related orbitides

Cyclic peptides are reported to have antibacterial, antifungal and other bioactivities. Orbitides are a class of cyclic peptide that are small, head-to-tail cyclized, composed of proteinogenic amino acids, and lack disulfide bonds; they are also known in several genera of the plant family Rutacea...

2020-10-14 | MTBLS1963 | MetaboLights
TranscriptomicsInhibition of Staphylococcus aureus biofilm formation by gurmarin, a plant-derived cyclic peptide
Staphylococcus aureus is an opportunistic pathogen capable of causing various infections ranging from superficial skin infections to life-threatening severe diseases, including pneumonia and sepsis. This bacterium is attached to biotic and abiotic surfaces and forms biofilms that are resistant to co...
ORGANISM(S): Staphylococcus aureus 
2022-09-21 | E-MTAB-12154 | biostudies-arrayexpress
GenomicsRapid discovery of cyclic peptide protein aggregation inhibitors through continuous selection HTS data
Rapid discovery of cyclic peptide protein aggregation inhibitors through continuous selection HTS data
PRJNA1170358 | ENA
ProteomicsDevelopment of Proteome Derived Cyclic Peptide Libraries via Ortho Phthalaldehyde Assisted Cyclization
This dataset contains raw LC–MS/MS data and associated search results generated for the identification and characterization of proteome-derived cyclic peptides produced via ortho-phthalaldehyde (OPA)-mediated macrocyclization. Cysteine-containing peptides derived from human proteome digests were sel...
ORGANISM(S): Homo sapiens (Human) 
2026-09-03 | PXD074548 | Pride
Cyclic peptide library Mass spectrometry Ortho-phthalaldehyde (opa) Igg-binding peptide Protein recognition 
GenomicsA Natural Cyclic Peptide Enhances Cytotoxic Th9 Differentiation and Antitumor Immunity
A Natural Cyclic Peptide Enhances Cytotoxic Th9 Differentiation and Antitumor Immunity
PRJNA1252720 | ENA
OtherRapid discovery of cyclic peptide protein aggregation inhibitors through continuous selection HTS data
We report a new platform for the rapid phenotypic selection of protein aggregation inhibitors from genetically encoded cyclic peptide libraries in E. coli based on phage-assisted continuous evolution (PACE). Here, we developed a new PACE-compatible selection for protein aggregation inhibition and em...
ORGANISM(S): Inovirus M13 
2024-10-25 | GSE279094 | GEO
GenomicsA Natural Cyclic Peptide Enhances Cytotoxic Th9 Differentiation and Antitumor Immunity (ATACseq)
A Natural Cyclic Peptide Enhances Cytotoxic Th9 Differentiation and Antitumor Immunity (ATACseq)
PRJNA1259798 | ENA
Genomics
Cyclic peptide diversity and biosynthesis of Rinorea bengalensis
PRJNA643891 | ENA
TranscriptomicsA Natural Cyclic Peptide Enhances Cytotoxic Th9 Differentiation and Antitumor Immunity
Adoptive cell therapy (ACT) relies on durable and functional T cells to mediate tumor clearance. Th9 cells are a metabolically fit CD4⁺ T cell subset with strong persistence but limited cytotoxicity. Here, we identify Endomelipaneptide A (EpA), a cyclic peptide from Ganoderma lucidum–associated endo...
ORGANISM(S): Mus musculus 
2025-11-28 | GSE295054 | GEO
GenomicsA Natural Cyclic Peptide Enhances Cytotoxic Th9 Differentiation and Antitumor Immunity (ATACseq)
Adoptive cell therapy (ACT) relies on durable and functional T cells to mediate tumor clearance. Th9 cells are a metabolically fit CD4⁺ T cell subset with strong persistence but limited cytotoxicity. Here, we identify Endomelipaneptide A (EpA), a cyclic peptide from Ganoderma lucidum–associated endo...
ORGANISM(S): Mus musculus 
2025-11-28 | GSE296515 | GEO
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