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ProteomicsChemical Genetic Identification of Cyclin-G-associated kinase (GAK) Substrates Reveals its Role in Regulating Na+/K+-ATPase and Sipa1L1 in Neurons
Recent genetic evidence implicates the serine/threonine kinase cyclin G-associated kinase (GAK) as a Parkinson’s disease risk. However, its role in neuronal function and many downstream effectors remain unclear. Employing a chemical genetics method, we show here that the sodium potassium pump (Na+...
ORGANISM(S): Mus musculus (Mouse) 
2019-01-07 | PXD011319 | Pride
Cyclin-g-associated kinase Sodium potassium pump Atp1a3 Gak 
GenomicsGlomerular microRNA data of the kidney podocyte-specific cyclin-G associated kinase (Gak) deficient mice
Glomerular microRNA data of the kidney podocyte-specific cyclin-G associated kinase (Gak) deficient mice
PRJNA665044 | ENA
GenomicsCell-cycle deregulation in diffuse large B-cell lymphoma promotes critical dependence on the cyclin-G associated kinase
Cell-cycle deregulation in diffuse large B-cell lymphoma promotes critical dependence on the cyclin-G associated kinase
PRJNA1173600 | ENA
UnknownIdentification and Optimization of 4-Anilinoquinolines as Inhibitors of Cyclin G Associated Kinase.
Not available
S-EPMC5914168 | biostudies-literature
UnknownStructural Basis for the Inhibition of Cyclin G-Associated Kinase by Gefitinib.
Not available
S-EPMC6129943 | biostudies-literature
UnknownSelective Inhibitors of Cyclin G Associated Kinase (GAK) as Anti-Hepatitis C Agents.
Not available
S-EPMC4431592 | biostudies-literature
TranscriptomicsGlomerular microRNA data of the kidney podocyte-specific cyclin-G associated kinase (Gak) deficient mice
Evidence for reduced expression of cyclin-G associated kinase (GAK) in glomeruli of chronic kidney disease patients was observed in the Nephroseq human database and was found to be associated with the decline in kidney function. To examine the role of GAK, a protein that functions to uncoat clathrin...
ORGANISM(S): Mus musculus 
2020-12-08 | GSE158384 | GEO
UnknownStructure of cyclin G-associated kinase (GAK) trapped in different conformations using nanobodies.
Not available
S-EPMC3957475 | biostudies-literature
UnknownCyclin G-associated kinase promotes microtubule outgrowth from chromosomes during spindle assembly.
Not available
S-EPMC2919828 | biostudies-literature
UnknownTowards the Development of an In vivo Chemical Probe for Cyclin G Associated Kinase (GAK).
Not available
S-EPMC6891286 | biostudies-literature
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