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TranscriptomicsTranscriptome sequencing of two macaques, crab-eating macaque and Indian rhesus macaque
Deep sequencing of mRNA from two macaques, crab-eating macaque and Indian rhesus macaque Analysis of ploy(A)+ RNA of different specimens:brain,ileum,kidney,liver,testes and white adipose for crab-eating macaque while brain,heart,,kidney,liver,quadriceps and testes for Indian rhesus macaque
ORGANISM(S): Macaca mulatta 
2011-10-13 | E-GEOD-29629 | biostudies-arrayexpress
TranscriptomicsTranscriptional comparison of cynomolgus macaques (Macaca fascicularis) following infection with Lassa or Lujo viruses
Microarray analysis of PBMC from cynomolgus macaques collected longitudinally over the course of infection with Lassa-Josiah, Lassa-Z132, Lassa-SorombaR, or Lujo viruses (n=3 animals/infection condition). 3 macaques from each group were infected intramuscularly with 10^4 PFU of Lassa-Josiah, Lassa-Z...
ORGANISM(S): Macaca fascicularis 
2014-08-29 | E-GEOD-49838 | biostudies-arrayexpress
TranscriptomicsComparative Pathogenesis of Three Human and Zoonotic SARS-CoV Strains in Cynomolgus Macaques
The severe acute respiratory syndrome (SARS) epidemic was characterized by increased pathogenicity in the elderly due to an early exacerbated innate host response. SARS-CoV is a zoonotic pathogen that entered the human population through an intermediate host like the palm civet. To prevent future in...
ORGANISM(S): Macaca mulatta 
2011-08-31 | E-GEOD-23955 | biostudies-arrayexpress
GenomicsInfinium Monkeys: Infinium 450K array for the Cynomolgus macaque (Macaca fascicularis) RRBS-seq
Infinium 450K is a hybridization array designed for the human genome, but the relative conservation between the macaque and human genomes makes its use in macaques feasible. We used the Infinium450K array to assay twelve Cynomolgus macaque muscle biopsies and compared it to Reduced Representation Bi...
ORGANISM(S): Macaca fascicularis 
2014-06-05 | E-GEOD-53593 | biostudies-arrayexpress
TranscriptomicsExpression data from the brain of cynomolgus macaques upon intrastriatal administration of baculoviral vectors
Recombinant insect baculoviral vectors efficiently transduce several types of cells in the brain and can possibly be used for gene therapy for brain disorders. To verify the suitability of using these viral vectors to develop gene therapy strategies in the brain, we evaluated immune reactions upon a...
ORGANISM(S): Macaca fascicularis 
2015-11-21 | E-GEOD-75264 | biostudies-arrayexpress
TranscriptomicsRNA-seq of of human (Homo sapiens), gorilla (Gorilla gorilla) and cynomolgus macaque (Macaca fascicularis) iPSC and iPSC-derived NPC cell lines
RNA-seq samples from 3 species across a differentiation from induced pluripotent stem cells to neural progenitor cells were generated to study gene expression evolution. Briefly, previously generated urinary stem cell derived iPSCs of 3 human (Homo sapiens) individuals (3 clones), 1 gorilla (Gorill...
ORGANISM(S): Homo sapiens 
2023-11-23 | E-MTAB-13494 | biostudies-arrayexpress
GenomicsCynomolgus macaques: Young vs Elder
Cynomolgus macaques: Young vs Elder
PRJNA824333 | ENA
TranscriptomicsBovine spongiform encephalopathy infection alters endogenous retrovirus expression in distinct brain regions of cynomolgus macaques (Macaca fascicularis)
Background: Prion diseases such as bovine spongiform encephalopathies (BSE) are transmissible neurodegenerative diseases which are presumably caused by an infectious conformational isoform of the cellular prion protein. Previous work has provided evidence that in murine prion disease the endogenous ...
ORGANISM(S): Macaca fascicularis 
2011-06-10 | E-GEOD-29818 | biostudies-arrayexpress
TranscriptomicsInteractome analysis of longitudinal pharyngeal infection of cynomolgus macaques by group A Streptococcus
Relatively little is understood about the dynamics of global host–pathogen transcriptome changes that occur during bacterial infection of mucosal surfaces. To test the hypothesis that group A Streptococcus (GAS) infection of the oropharynx provokes a host transcriptome response, we performed genom...
ORGANISM(S): Macaca fascicularis 
2010-03-18 | E-GEOD-20262 | biostudies-arrayexpress
TranscriptomicsCynomolgus macaque model of H7N9 influenza infection
The objective of this study is to characterize the response to newly emerged, highly pathogenic H7N9 influenza virus isolated from human patients in 2013 in China. This study examines the pathogenesis of H7N9 influenza in cynomolgus macaques. The study compares lung lesions to adjacent right lowe...
ORGANISM(S): Macaca fascicularis 
2014-07-22 | E-GEOD-48976 | biostudies-arrayexpress
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