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TranscriptomicsCynomolgus monkey testicular cDNAs for discovery of novel human genes
BACKGROUND: In order to contribute to the establishment of a complete map of transcribed regions of the human genome, we constructed a testicular cDNA library for the cynomolgus monkey, and attempted to find novel transcripts for identification of their human homologues. RESULT: The full-insert sequ...
ORGANISM(S): Homo sapiens 
2010-06-05 | E-GEOD-513 | biostudies-arrayexpress
TranscriptomicsA developmental coordinate of the spectrum of pluripotency among mice, monkeys, and humans
The epiblast (EPI) is the origin of all somatic and germ cells in mammals, and of the spectrum of pluripotent stem cells (PSCs) in vitro. To explore the ontogeny of human/primate pluripotency, we performed comprehensive single-cell RNA sequencing for pre- and post-implantation EPI development in cyn...
ORGANISM(S): Mus musculus 
2016-08-24 | E-GEOD-74767 | biostudies-arrayexpress
ProteomicsProteomic Atlas of Obesity and Type 2 Diabetes in Cynomolgus Monkeys
Obesity and type 2 diabetes (T2D) remain major global healthcare challenges and developing therapeutics necessitate using nonhuman primate models. Here, we present proteomic analyses of all the major organs of cynomolgus monkeys with spontaneous obesity or T2D in comparison to healthy controls.
ORGANISM(S): Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) 
2023-06-23 | PXD036423 | Pride
Obesity Cynomolgus monkeys Type 2 diabetes 
TranscriptomicsEffects of equol on gene expression in female cynomolgus monkey iliac arteries
Objective: To examine the effects of the phytoestrogen metabolite, equol, on gene expression in the monkey iliac artery. Design: Eight ovariectomized cynomolgus monkeys were on a high fat diet for 6.5 years. The left iliac artery was biopsied prior to randomization to equol (0.0237 g/100 g chow, ...
ORGANISM(S): Macaca fascicularis 
2014-03-11 | E-GEOD-37186 | biostudies-arrayexpress
TranscriptomicsRNA-seq of of human (Homo sapiens), gorilla (Gorilla gorilla) and cynomolgus macaque (Macaca fascicularis) iPSC and iPSC-derived NPC cell lines
RNA-seq samples from 3 species across a differentiation from induced pluripotent stem cells to neural progenitor cells were generated to study gene expression evolution. Briefly, previously generated urinary stem cell derived iPSCs of 3 human (Homo sapiens) individuals (3 clones), 1 gorilla (Gorill...
ORGANISM(S): Homo sapiens 
2023-11-23 | E-MTAB-13494 | biostudies-arrayexpress
GenomicsInfinium Monkeys: Infinium 450K array for the Cynomolgus macaque (Macaca fascicularis) RRBS-seq
Infinium 450K is a hybridization array designed for the human genome, but the relative conservation between the macaque and human genomes makes its use in macaques feasible. We used the Infinium450K array to assay twelve Cynomolgus macaque muscle biopsies and compared it to Reduced Representation Bi...
ORGANISM(S): Macaca fascicularis 
2014-06-05 | E-GEOD-53593 | biostudies-arrayexpress
TranscriptomicsATAC-seq of human (Homo sapiens) and cynomolgus macaque (Macaca fascicularis) iPSC and iPSC-derived NPC cell lines
ATAC-seq samples from 2 species and 2 cell types were generated to study cis-regulatory element evolution. Briefly, previously generated urinary stem cell derived iPS-cells (Homo sapiens) of 2 human individuals and fibroblast derived cynomolgus macaque iPSCs (Macaca fascicularis) of 2 individuals (...
ORGANISM(S): Macaca fascicularis 
2023-10-25 | E-MTAB-13373 | biostudies-arrayexpress
TranscriptomicsExpression profiling in Macaca fascicularis liver samples
The long-tailed macaque, also referred to as cynomolgus monkey (Macaca fascicularis), is one of the most important non-human primate animal models in basic and applied biomedical research. To improve the predictive power of primate experiments for humans, we determined the genome sequence of a Macac...
ORGANISM(S): Macaca fascicularis 
2011-08-24 | E-GEOD-30184 | biostudies-arrayexpress
GenomicsRNA sequencing of lung tissue of cynomolgus monkeys
RNA sequencing of lung tissue of cynomolgus monkeys
PRJNA630693 | ENA
ProteomicsPlasma proteomic of cynomolgus monkeys by caloric restriction (CR)
Plasma proteomic of cynomolgus monkeys by caloric restriction (CR)
ORGANISM(S): Macaca Fascicularis Fascicularis 
2024-11-27 | PXD058298 |
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