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MetabolomicsMetabolomic Profiling of Renal Cyst Fluid in Advanced ADPKD: Insights from Dialysis and Transplantation Cohorts

Background: Autosomal dominant polycystic kidney disease (ADPKD) is a hereditary disorder characterized by progressive renal cyst formation, often leading to end-stage kidney disease (ESKD). While urinary metabolomics in ADPKD has been extensively studied, the composition of renal cyst fluid, par...

2025-07-07 | MTBLS12372 | MetaboLights
ProteomicsDetermination of pancreatic cyst fluids peptidome and proteome
Determination of pancreatic cyst fluids (PCF) peptidome and proteome in 5 distinct patient groups: malignant (CAs), intraductal papillary mucinous neoplasms (IPMNs), mucinous cystic neoplasms (MCNs), serous cystic neoplasms (SCNs), and pseudocysts (PCs). The PCF <5kDa fraction, referred as the degra...
ORGANISM(S): Homo sapiens (Human) 
2019-01-14 | PXD005248 | Pride
Human Pancreas Cyst fluids Degradome Proteome Lc-ms/ms 
ProteomicsQuantitative Proteomic Analysis of Pancreatic Cyst Fluid Proteins Associated with Malignancy in Intraductal Papillary Mucinous Neoplasms
Intraductal papillary mucinous neoplasm (IPMN) is a benign tumor that grows within the pancreatic ducts characterized by the production of thick mucinous fluid by surrounding tumor cells. IPMN is the most important precursor lesion for pancreatic cancer that is the fourth most common cause of cancer...
ORGANISM(S): Homo sapiens (Human) 
2018-05-01 | PXD008302 | Pride
Ipmn dysplasia Mucinous cystic neoplasm (mcn) Biomarker candidates Pancreatic cyst fluid Intraductal papillary mucinous neoplasm (ipmn) Lc-ms/ms 
ProteomicsQuantitative Proteomic Profiling for Predicting Grade of Dysplasia in Intraductal Papillary Mucinous Neoplasm using Pancreatic Cyst Fluid
The increased number of pancreatic cyst lesions (PCLs) have been detected through the development of abdominal imaging techniques, such as computed tomography (CT), magnetic resonance imaging (MRI), and endoscopic ultrasound (EUS). However, accurate classification of cystic lesions is difficult beca...
ORGANISM(S): Homo sapiens (Human) 
2020-09-06 | PXD016127 | Pride
Mucinous cystic neoplasm (mcn) Pancreatic cyst fluid Biomarkers Intraductal papillary mucinous neoplasm (ipmn) Serous cystic neoplasm (scn) Lc-ms/ms 
ProteomicsComparative proteomics of Adult Paragominus kellikotti excretion/secretion products released in vitro or present in the lung cyst nodule
The aims of this study were to study ESPs to improve understanding of parasite-host interactions and to support the discovery of novel diagnostic or therapeutic targets. We used tandem mass-spectrometry to characterize the secretome of adult P. kellicotti flukes and to compare ESPs released during i...
ORGANISM(S): Paragominus Kellikotti 
2022-06-02 | MSV000089589 | MassIVE
UnknownEarly inflammatory response in epithelial ovarian tumor cyst fluids.
Not available
S-EPMC4302680 | biostudies-literature
UnknownCXCR2 agonists in ADPKD liver cyst fluids promote cell proliferation.
Not available
S-EPMC2956747 | biostudies-literature
ProteomicsMALDI_Immune reactive Proteins of Taenia solium cyst fluid
Here, in this objective by employing 2D_gel electrophoresis and NCC positive serum sample, we identified immune reactive proteins present in Taenia solium cyst fluid that were subsequently utilized for in-silico vaccine preparation.
ORGANISM(S): Cellular Organisms 
2024-07-29 | PXD044198 | JPOST Repository
UnknownMass Spectrometry-Based Comprehensive Analysis of Pancreatic Cyst Fluids.
Not available
S-EPMC6304507 | biostudies-literature
Genomicsuncultured bacterium strain:microbiome-homo sapiens | isolate:Pancreatic cyst fluid
Pancreatic cyst fluids constitutes a unique microbiological ecosystem
PRJNA357690 | ENA
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