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ProteomicsH2S-mediated S-sulfhydration coordinates autophagy and infection of the rice blast fungus
Hydrogen sulfide (H2S), a potent signaling molecule, regulates cellular activities in plants and mammals through S-sulfhydration, a post-translational modification. The role of H2S and its molecular targets in fungi, however, remain unclear. Our study demonstrates that H2S, synthesized by cystathion...
ORGANISM(S): Oryza sativa (Rice) 
2025-06-12 | PXD063170 | Pride
S-sulfhydration h2s atg18 magnaporthe oryzae 
UnknownL-Cysteine attenuates osteopontin-mediated neuroinflammation following hypoxia-ischemia insult in neonatal mice by inducing S-sulfhydration of Stat3.
Not available
S-EPMC9253102 | biostudies-literature
ProteomicsQuantitative profiling of protein sulfhydrome by the BTA-TMT
The redox-based modification of cysteine residues in proteins regulates their function in many biological processes. The gas molecule H2S has been shown to sulfhydrate redox sensitive cysteine residues resulting in an H2S-modified proteome known as the sulfhydrome. Tandem Mass Tags (TMT) multiplexin...
ORGANISM(S): Homo sapiens (Human) Mus musculus (Mouse) Rattus norvegicus (Rat) 
2020-03-09 | PXD015307 | Pride
Tmt Cysteine sulfhydration 
ProteomicsChemoproteomics reveals extensive cysteine S-sulfhydration in deep-sea hyperthermophilic archaea
Thermococcales are an order of archaea that inhabit the sulfur-rich, anaerobic environments of deep-sea hydrothermal vents. Their metabolism shifts toward the production of hydrogen sulfide (H₂S) in the presence of elemental sulfur. As a gaseous signaling molecule, H₂S primarily regulates biological...
ORGANISM(S): Thermococcus Eurythermalis 
2025-10-29 | PXD070017 |
UnknownDetection of protein S-sulfhydration by a tag-switch technique.
Not available
S-EPMC4306352 | biostudies-literature
UnknownQuantitative H2S-mediated protein sulfhydration reveals metabolic reprogramming during the integrated stress response.
Not available
S-EPMC4733038 | biostudies-literature
UnknownInteraction between hydrogen sulfide-induced sulfhydration and tyrosine nitration in the KATP channel complex.
Not available
S-EPMC4360042 | biostudies-literature
UnknownHydrogen sulfide mediates athero-protection against oxidative stress via S-sulfhydration.
Not available
S-EPMC5843340 | biostudies-literature
UnknownH2S- and Redox-State-Mediated PTP1B S-Sulfhydration in Insulin Signaling.
Not available
S-EPMC9917502 | biostudies-literature
UnknownPersulfide reactivity in the detection of protein s-sulfhydration.
Not available
S-EPMC3745995 | biostudies-literature
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