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ProteomicsCytohesin-2 is essential for the survival of mice and regulates Golgi volume and Function
Proteins of the cytohesin family are known for their guanine-nucleotide exchange factor function for ARF-GTPases, mainly for ARF1 and ARF6. While Arf1 and Arf6 deficiency results in embryonic lethality, in vivo functions of cytohesins are rarely described and mostly inconspicuous. We analyzed the ro...
ORGANISM(S): Mus musculus (Mouse) 
2026-01-27 | PXD073571 | Pride
Cytohesin-2 Arf-gtpases Golgi apparatus Protein secretion 
ProteomicsCytohesin-2 is essential for the survival of mice and regulates Golgi volume and function
Proteins of the cytohesin family are known for their guanine-nucleotide exchange factor function for ARF-GTPases, mainly for ARF1 and ARF6. While Arf1 and Arf6 deficiency results in embryonic lethality, in vivo functions of cytohesins are rarely described and mostly inconspicuous. We analyzed the ro...
ORGANISM(S): Mus musculus (Mouse) 
2026-01-26 | PXD063657 | Pride
Cytohesin-2 is essential for the survival of mice and regulates golgi volume and function 
UnknownARF-GEF cytohesin-2/ARNO regulates R-Ras and α5-integrin recycling through an EHD1-positive compartment.
Not available
S-EPMC4642859 | biostudies-literature
UnknownThe N termini of a-subunit isoforms are involved in signaling between vacuolar H+-ATPase (V-ATPase) and cytohesin-2.
Not available
S-EPMC3581410 | biostudies-literature
UnknownThe GEF Cytohesin-2/ARNO Mediates Resistin induced Phenotypic Switching in Vascular Smooth Muscle Cells.
Not available
S-EPMC7048779 | biostudies-literature
UnknownCytohesin-2/ARNO: A Novel Bridge Between Cell Migration and Immunoregulation in Synovial Fibroblasts.
Not available
S-EPMC8790574 | biostudies-literature
UnknownGRASP and IPCEF promote ARF-to-Rac signaling and cell migration by coordinating the association of ARNO/cytohesin 2 with Dock180.
Not available
S-EPMC2820421 | biostudies-literature
ProteomicsTwo-step peptide solubilization increases coverage in high-sensitivity nanoHILIC/MS/MS-based proteomics
Nanoscale hydrophilic-interaction chromatography coupled with tandem mass spectrometry (nanoHILIC/MS/MS) is a promising alternative to reversed-phase liquid chromatography (RPLC) for proteomics, but its application is limited by the poor solubility of peptides in organic solvent-rich sample solution...
ORGANISM(S): Homo Sapiens (human) Bos Taurus 
2025-05-08 | PXD059304 | JPOST Repository
UnknownDifferential effects of cytohesins 2 and 3 on beta1 integrin recycling.
Not available
S-EPMC2863229 | biostudies-literature
UnknownCybr, a cytokine-inducible protein that binds cytohesin-1 and regulates its activity.
Not available
S-EPMC122398 | biostudies-literature
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