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Lethal Cytokine Storm Post-mRNA Booster Vaccination
SARS-CoV2 infection leads to cardiac injury and dysfunction in 20-30% of hospitalized patients and higher rates of mortality in patients with pre-existing cardiovascular disease. Inflammatory factors released as part of the 'cytokine storm' are thought to play a critical role in cardiac dysfunction ...
ORGANISM(S): Homo sapiens (Human) 
2022-02-21 | PXD020994 | Pride
Human cardiac organoids to model COVID‐19 cytokine storm induced cardiac injuries
SPLEVs, a new therapeutic modality for cytokine storm syndromes
sn-RNAseq profiling of the impact of a cytokine storm model in human cardiac organoids
We developed conditions to model conditions of diastolic dysfunction caused by inflammatory factors in human cardiac organoids. Our organoid model is based on conditions promoting maturation (Mills et al., PNAS, 2017 and Voges et al., In Revision) and incorporating human pluripotent stem cell derive...
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