Sort   by:  
 Page size 
MetabolomicsLongitudinal multi-omics reveals subset-specific mechanisms underlying irritable bowel syndrome

The gut microbiome has been implicated in multiple human chronic gastrointestinal (GI) disorders. Determining its mechanistic role in disease has been difficult due to apparent disconnects between animal and human studies and lack of an integrated multi-omics view of disease-specific physiologica...

2020-09-08 | MTBLS1396 | MetaboLights
TranscriptomicsHuman enteroendcrine cell responses to infection with Chlamydia trachomatis
The aim of this study was to perform a microarray analysis of the response pattern of EEC from both large and small bowel to infection in vitro, using Chlamydia trachomatis infection as a model. Two human EEC lines: LCC-18, derived from a neuroendocrine colonic tumour, and CNDT-2, derived from a sma...
ORGANISM(S): Homo sapiens 
2014-06-03 | E-GEOD-58151 | biostudies-arrayexpress
UnknownHedgehog signalling pathway orchestrates angiogenesis in triple-negative breast cancers.

Background

Several evidences suggest a marked angiogenic dependency in triple-negative breast cancer (TNBC) tumorigenesis and a potential sensitivity to anti-angiogenic agents. Herein, the putative role of Hedgehog (Hh) pathway in regulating TNBC-dependent angiogenesis was investigated.

M...

S-EPMC5520095 | biostudies-literature
UnknownPersonalizing Cancer Pain Therapy: Insights from the Rational Use of Analgesics (RUA) Group.

Introduction

A previous Delphi survey from the Rational Use of Analgesics (RUA) project involving Italian palliative care specialists revealed some discrepancies between current guidelines and clinical practice with a lack of consensus on items regarding the use of strong opioids in treating...
S-EPMC8119556 | biostudies-literature
Sort   by:  
 Page size