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TranscriptomicsATAC-seq analysis of the day-night rhythm in chromatin accessibility in PCM1+ left ventricular cardiomyocyte nuclei
This study investigated differential chromatin accessibility at zeitgeber time (ZT) 0 denoting the start of the light/inactive period in mice compared to ZT12 (the start of the dark/active) period to obtain insights into diurnal changes in transcription factor binding and gene regulatory pathways in...
ORGANISM(S): Mus musculus 
2024-02-29 | E-MTAB-13696 | biostudies-arrayexpress
ProteomicsPhosphoproteomic analysis of IL-2 MSA and IL-12 MSA combination on T cell signaling
Engineered cytokine-based approaches for immunotherapy of cancer are poised to enter the clinic, with IL-12 being at the forefront. However, little is known about potential mechanisms of resistance to cytokine therapies. We found that orthotopic murine lung tumors were resistant to systemically deli...
ORGANISM(S): Mus musculus (Mouse) 
2024-01-26 | PXD044740 | Pride
Signaling T cell Cytokine 
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