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TranscriptomicsNext generation sequencing identifies discrete classes of box C/D snoRNAs featuring different ends and RNA binding protein dependency
The paired-end next-generation sequencing of all small RNAs of less than 200 nucleotides in length from four different human cell lines (SKOV3ip1, MCF-7, BJ-Tielf, INOF) allowed us to determine the exact sequence(s) and variations of human box C/D snoRNAs (small nucleolar RNAs), revealing processing...
ORGANISM(S): Homo sapiens 
2014-07-01 | E-GEOD-55946 | biostudies-arrayexpress
TranscriptomicsRNA-Seq of monoclonal cell lines after CRISPR/Cas9-mediated editing of box C/D snoRNA genes (SNORDs)
In this study monoclonal cell lines carrying mutations in snoRNA genes (SNORD74, SNORD75, SNORD77, SNORD80) were obtained. Next, whole transcriptome analysis of obtained cell lines was performed on an Illumina NextSeq 500 platform. RNA-seq libraries was constructed on PolyA mRNA-enriched fraction. T...
ORGANISM(S): Homo sapiens 
2019-10-14 | E-MTAB-8269 | biostudies-arrayexpress
ProteomicsSni445 recruits box C/D snoRNPs snR4 and snR45 to guide ribosomal RNA acetylation by Kre33
Eukaryotic ribosome synthesis is a highly complex, multistep process that is best characterized in the yeast Saccharomyces cerevisiae. It is orchestrated by over 200 ribosome assembly factors and 75 small nucleolar ribonucleoproteins (snoRNPs), which guide site-specific chemical modifications of pre...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2026-01-30 | PXD067909 | Pride
Box c/d snornp Yeast Kre33 Cytidine acetylation Ribosome biogenesis 
GenomicsComprehensive map of ribosomal 2′-O-methylation and C/D box snoRNAs in Drosophila melanogaster [Fib_KD_TGIRT-seq]
Comprehensive map of ribosomal 2′-O-methylation and C/D box snoRNAs in Drosophila melanogaster [Fib_KD_TGIRT-seq]
PRJNA978096 | ENA
GenomicsComprehensive map of ribosomal 2′-O-methylation and C/D box snoRNAs in Drosophila melanogaster [Tissues_TGIRT-seq]
Comprehensive map of ribosomal 2′-O-methylation and C/D box snoRNAs in Drosophila melanogaster [Tissues_TGIRT-seq]
PRJNA1008077 | ENA
GenomicsComprehensive map of ribosomal 2′-O-methylation and C/D box snoRNAs in Drosophila melanogaster [Fib_KD_RiboMeth-seq]
Comprehensive map of ribosomal 2′-O-methylation and C/D box snoRNAs in Drosophila melanogaster [Fib_KD_RiboMeth-seq]
PRJNA1008079 | ENA
GenomicsNext generation sequencing identifies discrete classes of box C/D snoRNAs featuring different ends and RNA binding protein dependency
The paired-end next-generation sequencing of all small RNAs of less than 200 nucleotides in length from four different human cell lines (SKOV3ip1, MCF-7, BJ-Tielf, INOF) allowed us to determine the exact sequence(s) and variations of human box C/D snoRNAs (small nucleolar RNAs), revealing processing...
ORGANISM(S): Homo sapiens 
2014-07-01 | GSE55946 | GEO
GenomicsSnoBIRD: A tool to identify C/D box snoRNAs and refine their annotation across all eukaryotes
SnoBIRD: A tool to identify C/D box snoRNAs and refine their annotation across all eukaryotes
PRJNA1228658 | ENA
TranscriptomicsComprehensive map of ribosomal 2′-O-methylation and C/D box snoRNAs in Drosophila melanogaster [Fib_KD_TGIRT-seq]
The majority of Nm modifications in eukaryotes are placed by Fibrillarin, a conserved methyltransferase belonging to a ribonucleoprotein complex guided by C/D box small nucleolar RNAs (C/D box snoRNAs). We built the first comprehensive map of Nm sites in Drosophila melanogaster rRNAs using two compl...
ORGANISM(S): Drosophila melanogaster 
2024-02-12 | GSE233853 | GEO
OtherComprehensive map of ribosomal 2′-O-methylation and C/D box snoRNAs in Drosophila melanogaster [Fib_KD_RiboMeth-seq]
The majority of Nm modifications in eukaryotes are placed by Fibrillarin, a conserved methyltransferase belonging to a ribonucleoprotein complex guided by C/D box small nucleolar RNAs (C/D box snoRNAs). We built the first comprehensive map of Nm sites in Drosophila melanogaster rRNAs using two compl...
ORGANISM(S): Drosophila melanogaster 
2024-02-12 | GSE241400 | GEO
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