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ProteomicsD6 PROTEIN KINASE plasma membrane polarity is dependent on a repeated CXX(X)P motif and serine phosphorylation
D6 PROTEIN KINASE (D6PK) is a polarly localized plasma membrane-associated kinase from Arabidopsis thaliana that activates polarly distributed PIN-FORMED (PIN) auxin transporters. D6PK traffics rapidly to and from the plasma membrane, independently from its PIN targets. D6PK plasma membrane associat...
ORGANISM(S): Arabidopsis thaliana (Mouse-ear cress) 
2024-05-23 | PXD037885 | Pride
Arabidopsis D6 protein kinase Phosphorylation Polarity 
TranscriptomicsAlteration of renal gene expression affected by atypical chemokine receptor D6 knockout in diabetic OVE26 (OVE) mice
The D6 receptor can bind and internalize inflammatory chemokines without activating intracellular pathways. D6 can reduce tissue inflammation, presumably by scavenging inflammatory chemokines. In diabetic kidney there is extensive inflammation but the possible role of the D6 receptor has never been ...
ORGANISM(S): Mus musculus 
2013-10-10 | E-GEOD-51205 | biostudies-arrayexpress
TranscriptomicsTemporal Gene Expression Patterns in the skin of D6 null and wild type mice after inflammation with the chemical irritant TPA
The chemokine decoy receptor D6 internalises and degrades inflammatory CC chemokines enabling resolution of inflammation. In D6 deficient mice (D6 KO), otherwise innocuous cutaneous inflammatory stimuli induce a grossly exaggerated inflammatory response that bears many similarities to human psoriasi...
ORGANISM(S): Mus musculus 
2013-05-28 | E-GEOD-46889 | biostudies-arrayexpress
UnknownD6 protein kinase in root xylem benefiting resistance to Fusarium reveals infection and defense mechanisms in tung trees.
Not available
S-EPMC8558330 | biostudies-literature
UnknownA small-molecule compound D6 overcomes EGFR-T790M-mediated resistance in non-small cell lung cancer.
Not available
S-EPMC8668973 | biostudies-literature
UnknownRapid translocation of NGR proteins driving polarization of PIN-activating D6 protein kinase during root gravitropism.
Not available
S-EPMC10942638 | biostudies-literature
TranscriptomicsEarly introduction of oral paricalcitol in renal transplant recipients
In stable renal transplant recipients with hyperparathyroidism, the vitamin D agonist paricalcitol reduces the level of proteinuria. Animal studies have indicated possible anti-fibrotic and anti-inflammatory effects of paricalcitol. We hypothesised that early introduction of paricalcitol in de novo ...
ORGANISM(S): Homo sapiens 
2017-09-01 | E-GEOD-83486 | biostudies-arrayexpress
TranscriptomicsM Costa endothelial diff protocol
To test our hypothesis that human embryonic stem cell-derived endothelial cells(hESC-ECs) represent their in vivo counterparts, we performed transcriptional profiling experiments in which we compared the gene expression profiles of d6 CD34+KDR+ cells, d12-14 hESC-ECs and human umbilical vein endothe...
ORGANISM(S): Homo sapiens 
2012-11-01 | E-MEXP-3709 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse embryonic stem (ES) cells differentiated for 6 days samplesed at 24 hour timepoints (d1-d6) vs undifferentiated cells (d0)
Mouse ES cells were differentiated for 6 days. Undifferentiated cells (d0) were compared to cells harvested at 24 hour timepoints (d1-d6).
ORGANISM(S): Mus musculus 
2005-08-31 | E-MEXP-304 | biostudies-arrayexpress
ModelsLevchenko2000_MAPK_noScaffold
MAPK cascade in solution (no scaffold) Description This model describes a basic 3- stage Mitogen Activated Protein Kinase (MAPK) cascade in solution. This cascade is typ...
2024-09-02 | BIOMD0000000011 | BioModels
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