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MetabolomicsLongitudinal metabolomics and lipidomics analyses reveal markers of envenoming by Bothrops asper and Daboia russelii in an experimental murine model

Longitudinal metabolomics and lipidomics analysis was carried out in the blood plasma of mice injected intramuscularly with venoms of the viperid species Bothrops asper and Daboia russelii. Blood samples were collected 1, 3, 6 and 24 h after venom injection, and a control group ...

2022-09-21 | MTBLS5430 | MetaboLights
ProteomicsThe Arabian cousin: Comparative venomics of Daboia palaestinae and Daboia russelii
In this study, to unravel the influence of phylogenetic divergence and biogeography in shaping the composition and activity of Daboia venoms, we comparatively investigated the venoms of D. russelii from western India and D. palaestinae from Israel.
ORGANISM(S): Daboia russelii Daboia palaestinae 
2023-03-11 | PXD031190 | Pride
Daboia palaestinae  daboia russelii  venomics  transcriptomics  preclinical assessment 
ProteomicsBiogeographic venom variation in medically important Indian snakes and the inadequacy of antivenom therapy in snakebite hotspots
The project aims at investigating the snake venom variability of Daboia russelii populations from five different biogeographic zones across India.
ORGANISM(S): Daboia russelii 
2021-02-26 | PXD021060 | Pride
Venom variation Snake venoms Daboia russelii venom Venomics 
ProteomicsProteomic analysis of Daboia russelli venom samples from Burdwan and Nadia districts of West Bengal, eastern India
Russell’s viper (Daboia russelii) (RV), a category I medically important snake as well as a member of the “Big Four”, is responsible for a heavy toll of snake bite mortality and morbidity in Indian sub-continent. Epidemiological studies suggest highest incidence of RV envenomation in eastern India (...
ORGANISM(S): Daboia russelii 
2018-07-16 | PXD008607 | Pride
Shotgun proteomics Snake venom Lc-ms/ms 
OtherMapping the immune cell microenvironment by digital spatial profiling in muscle tissue injected with the venom of Daboia russelii
Pathological and inflammatory events in muscle after injection of snake venoms vary in different regions of the affected tissue and at different time intervals. In order to study such heterogeneity in the immune cell microenvironment, a murine model of muscle necrosis based on the injection of the v...
ORGANISM(S): Mus musculus 
2023-03-07 | GSE222977 | GEO
UnknownBiogeographic venom variation in Russell's viper (Daboia russelii) and the preclinical inefficacy of antivenom therapy in snakebite hotspots.
Not available
S-EPMC7993602 | biostudies-literature
UnknownThe Middle Eastern Cousin: Comparative Venomics of Daboia palaestinae and Daboia russelii.
Not available
S-EPMC9696752 | biostudies-literature
ProteomicsFrom birth to bite: the evolutionary ecology of India's medically most important snake venoms
Venoms of N. naja and D. russelii individuals of various developmental stages, including neonates (<30 days), juveniles (between 1 to 12 months), and mature individuals (>36 months), were sampled with permission from the state forest department of Karnataka. 226 individuals and 9 clutches were exami...
ORGANISM(S): Naja naja Daboia russelii 
2024-08-10 | PXD046781 | Pride
Thermofisher orbitrap fusion mass spectrometry Snake venom Daboia russelii Venom proteomics Naja naja Ontogeny 
GenomicsMapping the immune cell microenvironment by digital spatial profiling in muscle tissue injected with the venom of Daboia russelii
Mapping the immune cell microenvironment by digital spatial profiling in muscle tissue injected with the venom of Daboia russelii
PRJNA924326 | ENA
TranscriptomicsTranscription profiling of human cell line THP-1 cells exposed to Daboiatoxin and cytokines involved in melioidosis caused by B. pseudomalli
Gene expression profiles of human cell (THP-1) lines exposed to a novel Daboiatoxin (DbTx) isolated from Daboia russelli russelli, and specific cytokines and inflammatory pathways involved in acute infection caused by Burkholderia pseudomallei. Experiment Overall Design: 1. Group I:- Human monocytic...
ORGANISM(S): Homo sapiens 
2009-04-04 | E-GEOD-7577 | biostudies-arrayexpress
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