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TranscriptomicsMicroglia treatment with C6 glioma-conditioned medium or with LPS
Several independent microglia preparations performed on different days were plated onto wells of 24-well plates, and either left untreated (control), treated with the C6 glioma-conditioned medium, or treated with LPS.
For each culture condition, a number of RNA samples were prepared, with each sa...
ORGANISM(S): Rattus norvegicus 
2012-12-14 | E-MEXP-2466 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of in rat brains 6-48 hours after MCAO stroke incudtion with and without FK506 drug treatment
Analysis of changes in gene expression induced by a transient (90') middle cerebral artery occulsion, at several time points post stroke induction, with the effect of a treatment with the drug FK506 studied at a single time point.
ORGANISM(S): Rattus norvegicus 
2010-06-19 | E-MEXP-2222 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of primary hippocampal neurons isolated from mouse E17 embryos and undergoing differentiation in the culture for 7h, 18h, 33h, 72h, 8 days, 12 days (at which time points the RNA was extracted) vs RNA isolated from a newborn brain
A time-course experiment, in which the gene expression in the primary hippocampal neurons isolated from E17 embryos and undergoing differentiation in the culture for 7h, 18h, 33h, 72h, 8 days, 12 days (at which time points the RNA was extracted) was compared by competitive hybridization with a commo...
ORGANISM(S): Mus musculus 
2003-06-01 | E-MEXP-11 | biostudies-arrayexpress
TranscriptomicsTime-series transcription profiling by array of rat microglia treated with C6 glioma-conditioned medium.
Several independent microglia preparations performed on different days were plated onto wells of 24-well plates, and either left untreated (control), treated with the C6 glioma-conditioned medium (GCM). RNA samples were prepared at 6, 24 and 48 hours from the start of the treatment, as well as from ...
ORGANISM(S): Rattus norvegicus 
2018-10-03 | E-MTAB-6143 | biostudies-arrayexpress
TranscriptomicsMicroarray gene expression profiling of microglia from control and C6 glioma tumor-bearing brain hemisphere in the rat.
The aim of the experiment was to identify differences in gene expression in the microglia due to the presence of a brain tumor, at 14 days after a stereotactic injection of 5 x 10E4 rat C6 glioma cells into the right striatum of the rat. The control (naive) animals were left untreated. The brain hem...
ORGANISM(S): Rattus norvegicus 
2018-01-22 | E-MTAB-5050 | biostudies-arrayexpress
TranscriptomicsMicroarray gene expression profiling of the whole brain hemisphere in the rats with C6-glioma tumor.
The aim of the experiment was to identify differences in gene expression in the whole brain hemisphere due to the presence of a brain tumor. At 21 days after a stereotactic injection of 5 x 10E4 rat C6 glioma cells into the right striatum of the rat the animals were sacrificed and the tumor-bearing...
ORGANISM(S): Rattus norvegicus 
2017-08-31 | E-MTAB-5049 | biostudies-arrayexpress
GenomicsChIP-Seq for TCF7L2 in adult mouse thalami
We used chromatin immunoprecipitation combined with DNA sequencing to identify TCF7L2 localization on thalamic genome. We report that among putative TCF7L2 direct targets are thalamic terminal effector genes.
ORGANISM(S): Mus musculus 
2020-07-24 | E-MTAB-9384 | biostudies-arrayexpress
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