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TranscriptomicsGenomic profile of foamy and non-foamy granuloma macrophages from fat-fed ApoE null mice or control mice fed a normal diet
Formation of foam cell macrophages (FCMs), which sequester extracellular modified lipids, is a key event in atherosclerosis. How lipid loading affects macrophage phenotype is controversial, with evidence suggesting either pro- or anti-inflammatory consequences. To investigate this further, we compar...
ORGANISM(S): Mus musculus 
2015-07-23 | E-GEOD-70126 | biostudies-arrayexpress
UnknownComprehensive analysis of liver macrophage composition by flow cytometry and immunofluorescence in murine NASH.
Not available
S-EPMC8102804 | biostudies-literature
UnknownClaw morphometrics in monitor lizards: Variable substrate and habitat use correlate to shape diversity within a predator guild.
Not available
S-EPMC6053582 | biostudies-literature
UnknownQuantitative heterodonty in Crocodylia: assessing size and shape across modern and extinct taxa.
Not available
S-EPMC6397764 | biostudies-literature
TranscriptomicsChronic Hypoxia predicts Poor Prognosis in Hepatocellular Carcinoma
Background - Hepatocellular carcinomas (HCCs) are heterogeneous tumors with respect to etiology, cell of origin and biology. The course of the disease is unpredictable and is in part dependent on the tumor microenvironment. One of the microenvironmental factors is hypoxia, which is known to promote ...
ORGANISM(S): Homo sapiens 
2010-07-20 | E-GEOD-15366 | biostudies-arrayexpress
TranscriptomicsPrediction of lymph node involvement in breast cancer from primary tumor tissue using gene expression profiling and miRNAs.
Lymph node involvement is the most important prognostic factor in breast cancer, but little is known about the underlying molecular changes. First, to identify a molecular signature associated with nodal metastasis, gene expression analysis was performed on a homogeneous group of 96 primary breast t...
ORGANISM(S): Homo sapiens 
2011-02-04 | E-GEOD-23177 | biostudies-arrayexpress
TranscriptomicsGene expression profiling of NSCLC cell lines upon TGFb-induced epithelial-mesenchymal transition (EMT)
Epithelial-mesenchymal transition has been implicated in tumor metastasis, cancer drug resistance and cancer stem cell features. In this study, we examined gene expression profiles of three non-small cell lung cancer cell lines, before and after experimentally induced EMT. We modeled epitheial-mese...
ORGANISM(S): Homo sapiens 
2014-11-19 | E-GEOD-49644 | biostudies-arrayexpress
TranscriptomicsIntrinsic Gene Expression Profiles of Gliomas are a Better Predictor of Survival than Histology
Histological classification of gliomas guides treatment decisions. Because of the high interobserver variability, we aimed to improve classification by performing gene expression profiling on a large cohort of glioma samples of all histological subtypes and grades. The seven identified intrinsic mol...
ORGANISM(S): Homo sapiens 
2010-04-26 | E-GEOD-16011 | biostudies-arrayexpress
UnknownTranscriptomic profiling of adjuvant colorectal cancer identifies three key prognostic biological processes and a disease specific role for granzyme B.
Not available
S-EPMC8719661 | biostudies-literature
UnknownHER2 is not a cancer subtype but rather a pan-cancer event and is highly enriched in AR-driven breast tumors.
Not available
S-EPMC5791377 | biostudies-literature
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