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TranscriptomicsTranscriptome analysis of the Tap efflux pump mutant in Mycobacterium bovis BCG.
We used DNA microarrays to define the physiological roles of the Tap efflux pump in M. bovis BCG during the exponential and the stationary phase of in vitro growth. For this purpose we constructed a M. bovis BCG strain in which the tap gene was inactivated by the insertion of a hygromycin resistance...
ORGANISM(S): Mycobacterium bovis BCG 
2011-12-30 | E-GEOD-32249 | biostudies-arrayexpress
GenomicsSMiLE-seq sequencing data (illumina) of human transcription factors profiled in the Codebook/GRECO-BiT collaboration
We assayed 284 human transcription factors (TFs) for DNA binding using selective microfluidics-based ligand enrichment followed by sequencing (SMiLE-seq). These experiments were part of the Codebook/GRECO-BiT collaboration aiming to identify the DNA binding sites of yet-uncharacterized TFs. All data...
ORGANISM(S): synthetic construct 
2024-11-11 | E-MTAB-14598 | biostudies-arrayexpress
GenomicsMethylation-sensitive SMiLE-seq sequencing data (illumina) of human transcription factors profiled in the Codebook/GRECO-BiT collaboration
We assayed 114 human transcription factors (TFs) for DNA binding using methylation-sensitive selective microfluidics-based ligand enrichment followed by sequencing (meSMiLE-seq). Across 23 experiments, we identified DNA binding sites for 48 TFs. Among these, 13 showed aversion towards methylated DNA...
ORGANISM(S): synthetic construct 
2024-11-11 | E-MTAB-14597 | biostudies-arrayexpress
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