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ProteomicsThe colitis risk gene C1orf106 (ROCS) regulates epithelial adherens junction stability
Mohanan V, Nakata T, Desch N, L�vesque C, Boroughs A, Guzman G, Cao Z, Creasey E, Yao J, Boucher G, Charron G, Bhan AK, Schenone M, Carr SA, Reinecker HC, Daly MJ, Rioux JD, Lassen KG, Xavier RJ. Science 2018. Single nucleotide polymorphisms in C1orf106 are associated with increased risk of inflamma...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2018-01-16 | MSV000081941 | MassIVE
TranscriptomicsThe role of carbon starvation in the induction of enzymes that degrade plant-derived carbohydrates in Aspergillus niger
Fungi are an important source of enzymes for saccharification of plant polysaccharides and production of biofuels. Understanding of the regulation and induction of expression of genes encoding these enzymes is still incomplete. To explore the induction mechanism, we analysed the response of the indu...
ORGANISM(S): Aspergillus niger 
2014-08-22 | E-GEOD-57315 | biostudies-arrayexpress
MetabolomicsA conserved metabolic signature associated with response to fast-acting antimalarial agents

Characterizing the mode of action of antimalarial compounds that emerge from high-throughput phenotypic screens is central to understanding how parasite resistance to these drugs can emerge. Here, we have employed untargeted metabolomics to inform on the mechanism of action of antimalarial leads ...

2023-09-27 | MTBLS6580 | MetaboLights
UnknownCryophysiology of coral microfragments: effects of chilling and cryoprotectant toxicity.
Not available
S-EPMC11562774 | biostudies-literature
UnknownCryopreservation and revival of Hawaiian stony corals using isochoric vitrification.
Not available
S-EPMC10447501 | biostudies-literature
TranscriptomicsComparison of undifferentiated ES cell lines HM1, IMT11, SHBL6.3
3 different ES cell lines were compared in order to determine whether there are significant expression profile differences between ES cell lines, or whether the constraints of maintaining pluripotency in culture force a similar expression profile on cell lines derived from disparate sources. Our res...
ORGANISM(S): Mus musculus 
2007-08-03 | E-GEOD-8625 | biostudies-arrayexpress
ProteomicsCharacterization of PEAK3 pseudokinase as a pro-migratory and -invasive member of New Kinase Family 3
The New Kinase Family 3 (NKF3) of pseudokinases comprises PEAK1 and PEAK2 as well as the recently-identified PEAK3. PEAK1/2 play fundamental roles in regulating tyrosine kinase signal output and oncogenesis, while PEAK3 remains poorly-characterized. Here we demonstrate that PEAK3 undergoes homotypic...
ORGANISM(S): Homo sapiens (Human) 
2022-03-14 | PXD023687 | Pride
Nkf3/ peak1 (sgk269)/ peak2 (sgk223 Pragmin)/ peak3/brest cancer 
GenomicSTAMPEED: Northern Finland Birth Cohort 1966 (NFBC1966)

The Northern Finland Birth Cohorts program (NFBC) was initiated in the 1960s in the two northernmost provinces of Finland to study risk factors involved in pre-term birth and intrauterine growth retardation, and the consequences of these early adverse events on subsequent morbidity and mortality....

phs000276 | dbGaP
UnknownA missense variant in SLC39A8 confers risk for Crohn's disease by disrupting manganese homeostasis and intestinal barrier integrity.
Not available
S-EPMC7682327 | biostudies-literature
UnknownMDP: A Deinococcus Mn2+-Decapeptide Complex Protects Mice from Ionizing Radiation.
Not available
S-EPMC4976947 | biostudies-literature
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