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ProteomicsFrequent ZNF217 mutations lead to transcriptional deregulation of interferon signal transduction via altered chromatin accessibility in B cell lymphoma (Phospho-Proteome)
Recent exome-wide studies discovered frequent somatic mutations in the epigenetic modifier ZNF217 in primary mediastinal B cell lymphoma (PMBCL) and related disorders. As functional consequences of ZNF217 alterations remain unknown, we comprehensively evaluated their impact in PMBCL. Targeted sequen...
ORGANISM(S): Homo sapiens (Human) 
2024-01-26 | PXD040928 | Pride
Znf217 Phosphoproteome Pmbcl Non-hodgkin lymphoma Genetics Mutation 
ProteomicsFrequent ZNF217 mutations lead to transcriptional deregulation of interferon signal transduction via altered chromatin accessibility in B cell lymphoma (Global Proteome and PPI)
Recent exome-wide studies discovered frequent somatic mutations in the epigenetic modifier ZNF217 in primary mediastinal B cell lymphoma (PMBCL) and related disorders. As functional consequences of ZNF217 alterations remain unknown, we comprehensively evaluated their impact in PMBCL. Targeted sequen...
ORGANISM(S): Homo sapiens (Human) 
2024-01-26 | PXD034337 | Pride
Znf217 Pmbcl Non-hodgkin lymphoma Genetics Precision medicine Mutation Copy-number aberration 
UnknownA degradation-sensitive anionic trypsinogen (PRSS2) variant protects against chronic pancreatitis.
Not available
S-EPMC2746914 | biostudies-literature
UnknownA recurrent 11q aberration pattern characterizes a subset of MYC-negative high-grade B-cell lymphomas resembling Burkitt lymphoma.
Not available
S-EPMC3931189 | biostudies-literature
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