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GenomicsGenes expression profile in BMDM challenging with S1P or DAMPs
Genes expression profile in BMDM challenging with S1P or DAMPs
PRJNA796619 | ENA
ProteomicsAlteration of DAMPs and regulated cell death under hyperlipidemic stress
We hypothesize that DAMPs and non-apoptotic regulated cell death processes are critical players of artery plaque progression with inadequate response to lipid-lowering treatment. Using high performant LC-MS/MS proteomic analysis we aim to uncover the silent mechanisms that govern the existing residu...
ORGANISM(S): Oryctolagus cuniculus (Rabbit) 
2022-02-22 | PXD026379 | Pride
Regulated cell death Proteomics Mass spectrometry Damps 
ProteomicsLymphatic platelet thrombosis limits bone repair by precluding lymphatic transporting DAMPs
In the musculoskeletal system, lymphatic vessels (LVs), which are interdigitated with blood vessels, travel and form an extensive transport network. Blood vessels in bone regulate osteogenesis and hematopoiesis, however, whether LVs in bone affect fracture healing is unclear. Here, we investigated t...
ORGANISM(S): Rattus Norvegicus 
PXD056584 |
GenomicsTranscriptomic changes in macrophages induced by damage-associated molecular patterns (DAMPs)
Transcriptomic changes in macrophages induced by damage-associated molecular patterns (DAMPs)
PRJNA632501 | ENA
ProteomicsLabel-free proteomic analysis of apoptotic, necrotic and necroptotic DAMPs from HNSCC cells
Necroptosis is a newly discovered form of programmed cell death (PCD) showing necrotic features, including membrane permeabilization and the release of damage-associated molecular patterns (DAMPs). Studies have revealed both its tumorigenic role and therapeutic potential in various cancers, yet its ...
ORGANISM(S): Homo Sapiens 
PXD035379 |
GenomicsEffects of ferroptotic endothelial cell DAMPs on pulmonary artery smooth muscle cells
Effects of ferroptotic endothelial cell DAMPs on pulmonary artery smooth muscle cells
PRJNA1160921 | ENA
TranscriptomicsGenes expression profile in BMDM challenging with S1P or DAMPs
To explore the differently expressed genes in BMDM after the treatment with S1P or DAMPs (Damage associated molecular patterns). BMDM cells were incubated with apoptotic cell culture medium (ACM) or S1P (500nM) for 24 hours before harvest for RNA extraction. ACM generated from palmitic acid treated ...
ORGANISM(S): Mus musculus 
2022-12-06 | GSE193577 | GEO
GenomicsDAMPs drive Fibroinflammatory Changes in the glaucomatous ONH
DAMPs drive Fibroinflammatory Changes in the glaucomatous ONH
PRJNA1129064 | ENA
TranscriptomicsTranscriptomic changes in macrophages induced by damage-associated molecular patterns (DAMPs)
Dead cell-derived molecules, typically called as damage-accociated molecular patterns (DAMPs), have been shown to evoke inflammatory responses. Accordingly, it becomes increasingly clear that DAMPs play important role in pathogenesis of multiple diseases including inflammatory diseases and cancer. T...
ORGANISM(S): Mus musculus 
2021-05-21 | GSE150465 | GEO
Genomics
Transcriptomic alterations induced by necroptotic DAMPs
PRJNA848011 | ENA
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