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TranscriptomicsHost cell-free growth of the Q fever bacterium Coxiella burnetii
The inability to propagate obligate intracellular pathogens under axenic (host cell-free) culture conditions imposes severe experimental constraints that have negatively impacted progress in understanding pathogen virulence and disease mechanisms. Coxiella burnetii, the causative agent of human Q (Q...
ORGANISM(S): Coxiella burnetii 
2010-06-20 | E-GEOD-13338 | biostudies-arrayexpress
UnknownThe Recent Evolution of a Maternally-Inherited Endosymbiont of Ticks Led to the Emergence of the Q Fever Pathogen, Coxiella burnetii.
Not available
S-EPMC4433120 | biostudies-literature
TranscriptomicsComparison of testis transcriptome changes resulting from mutations in dany and representative meiotic arrest genes
The Drosophila gene dany is expressed specifically in spermatocytes and encodes a nuclear protein with similarity to the products of the genes distal antenna (dan) and distal antenna-related (danr). Loss of dany function results in male sterility. Mutant spermatocytes fail to differentiate similar a...
ORGANISM(S): Drosophila melanogaster 
2016-07-28 | E-GEOD-76298 | biostudies-arrayexpress
MetabolomicsMetabolomics Study of Serum and Urine Samples Reveals Metabolic Pathways and Biomarkers Associated with Pelvic Organ Prolapse
Pelvic organ prolapse (POP) is a common medical condition among women and involves complicated diagnostics and controversial surgical management. The exact molecular mechanism underlying POP is poorly understood, especially at the metabolism level. To explore the metabolic mechanism underlying POP a...
2019-08-14 | MTBLS1033 | MetaboLights
UnknownCoenzyme Q headgroup intermediates can ameliorate a mitochondrial encephalopathy.
Not available
S-EPMC12422950 | biostudies-literature
UnknownRapid identification of chemical profiles in vitro and in vivo of Huan Shao Dan and potential anti-aging metabolites by high-resolution mass spectrometry, sequential metabolism, and deep learning model.
Not available
S-EPMC11518704 | biostudies-literature
UnknownToward a scientific understanding of the effectiveness, material basis and prescription compatibility of a Chinese herbal formula Dan-hong injection.
Not available
S-EPMC5385876 | biostudies-literature
UnknownTherapeutic effects of traditional Chinese medicine Hua-Feng-Dan in a rat model of ischemic stroke involve renormalization of gut microbiota.
Not available
S-EPMC11808003 | biostudies-literature
ProteomicsStaphylococcus aureus linezolid processing proteomic data
Exponentially growing S.aureus ATCC 25923 was treated with linezolid (LZD) at concentrations of 1/2× MIC, 1× MIC, and 5× MIC, or an equivalent amount of DMSO for 1 hour. The bacteria were pelleted by centrifugation and washed twice with saline. The samples were then re-suspended in bacteria lysis bu...
ORGANISM(S): Staphylococcus aureus 
2023-12-11 | PXD046938 | Pride
S.aureus linezolid 
MetabolomicsCamel milk exosomes alleviate high-fat diet-induced metabolic dysfunction-associated steatotic liver disease and are associated with remodeling of the gut microbiota and hepatic metabolome
Camel milk-derived exosomes (CM-exos) are bioactive, yet their role in metabolic dysfunction-associated steatotic liver disease (MASLD) is unknown. We evaluated oral CM-exos in high-fat diet-induced MASLD mice, assessing metabolic parameters, gut microbiota, colonic short-chain fatty acids (SCFAs), ...
2026-10-27 | MTBLS16168 | MetaboLights
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