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Proteins bound to the IFI44L promoter were screened through DNA pull-down and mass spectrometry, and further proteins with transcriptional functions were screened through bioinformatics.
ORGANISM(S): Homo sapiens (Human) 
2026-02-09 | PXD065618 | Pride
Using ssRNA-seq, we examined the alteration of transcription profiles in the nucleus accumbens of methamphetamine-sensitized mice. Methamphetamine was a commonly abused psychostimulant. Repeated exposure to methamphetamine elicited long-lasting cellular and molecular changes, including the aberrant ...
ORGANISM(S): Mus musculus 
Chronic mountain sickness (CMS) is a progressive incapacitating syndrome induced by lifelong exposure to hypoxia. In the present study, proteomic analysis was used to identify the differential expression proteins (DEPs) and then evaluate the potential biomarkers between CMS and non-CMS groups. A tot...
ORGANISM(S): Homo Sapiens 
2020-10-22 | PXD022139 |
Although the landscape of epigenomic and transcriptomic regulation during human pre-implantation development has been depicted by applying single-cell sequencing, the investigation of embryonic proteome is almost unrevealed due to the insufficient input quantity from precious human embryonic samples...
ORGANISM(S): Homo Sapiens 
Here, by state-of-the-art mass spectrometry-based quantitative proteomic technology, we systematically screened the potential neo-substrates of a novel thalidomide derived cereblon modulator CC-885.
ORGANISM(S): Homo Sapiens 
2020-01-11 | PXD017071 |
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